Propineb
Basic information
- CAS
12071-83-9- Standard SMILES
CC(CNC(=S)[S-])NC(=S)[S-].[Zn+2]- InChIKey
KKMLIVYBGSAJPM-UHFFFAOYSA-L- Molecular formula
- C5H8N2S4Zn
- Average molar mass
- 289.8 g/mol
- Monoisotopic mass
- 287.886175
Overview
Propineb is a polymeric complex of zinc with the propylene 1,2-bis(dithiocarbamate) anionic ligand. A fungicide, it is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grapes, tomatoes, potatoes, berries, citrus, rice and tea. It has a role as an antifungal agrochemical. It is a macromolecule, a zinc coordination entity and a dithiocarbamate salt. It contains a propylene 1,2-bis(dithiocarbamate).
Names & identifiers
- Preferred name
- Propineb
- IUPAC
- zinc N-[1-(sulfidocarbothioylamino)propan-2-yl]carbamodithioate
- English name
- Propineb
- Molecular formula
- C5H10N2S4
- Molecular weight
- 226.41
Names & synonyms
PropinebAntracol12071-83-9MethylzinebMezinebPropinebeAironeTaifenBayer 46131DTXSID1052741Zinc propylene bisdithiocarbamateBAY 46131
Show more names
(1-methyl-1,2-ethanediyl)bis-carbamodithioic acid zinc complexlh30/zlh3012KORUNEBENERCOLAGROCOL
Zinc 1,2-propylene bisdithiocarbamatePropylenebis(dithiocarbamato)zincBAYER-46131CHEBI:81755003VPM353KB-5078propynebTsipromat
Database identifiers
- CAS
12071-83-9、9016-72-2- PubChem CID
- 6100711
- ChEBI
CHEBI:81755- UNII
- 003VPM353K
- EC Number
- 235-134-0、620-365-5
Properties
Computed structural properties
- Topological polar surface area
- 90.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 148
Experimental & physicochemical properties
Pesticides
Fungicides
Active substance -> EU Pesticides database: Not approved
Pesticides -> Dithiocarbamates (Pesticide)
Endocrine DisruptorsPotential endocrine disrupting compound
Vapor Pressure0.0000016 [mmHg]
Physical DescriptionWhite to yellowish solid; [Merck Index] Yellow solid; [MSDSonline]
Physicochemical properties
- Melting point
- 157 · 157-159°C
- storage temp.
- 0 · 0-6°C
- solubility
- DMSO (Slightly, Heated)
- form
- Solid
- color
- Off-White to Light Beige
- Merck
- 13 · 13,7911
- Major Application
- agricultureenvironmental
- InChI
- 1S/C5H10N2S4.Zn/c1-3(7-5(10)11)2-6-4(8)9;/h3H,2H2,1H3,(H2,6,8,9)(H2,7,10,11);/q;+2/p-2
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
P260, P261, P271, P272, P273, P280, P302+P352, P304+P340, P317, P319, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Not Classified
Aggregated GHS information provided per 43 reports by companies from 4 notifications to the ECHA C&L Inventory.
Warning
Hazard information
Regulatory Information
Chemical: Zinc, [[(1-methyl-1,2-ethanediyl)bis(carbamodithioato)](2-)]-, homopolymer
Commission Regulation No 844/2012
03/39/EC, Reg. (EU) 2016/2016, Reg. (EU) 2018/309, Reg. (EU) No 540/2011, Reg. (EU) No 823/2012, Reg.(EU) No 84/2018
REACH registered substance: Zinc, [[(1-methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]-, homopolymer (EC: 620-365-5)
Propineb: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards Summary
Skin sensitization reported in a farmworker; [Kanerva, p. 1847] Non-irritating to skin or eyes of rabbits; Sensitizing in guinea pig maximization test, but not sensitizing in Buehler test on guinea pigs; [IUCLID] Has goitrogenic effect in rats, but effect not reported in rabbits or dogs; Dogs fed 75 mg/kg for 2 years had no adverse effects; No reports of skin sensitization in humans; Unlikely to present acute hazard in normal use. [WHO-JMPR] May cause irritation; [MSDSonline]
Hazard Classes and Categories
Not Classified
Skin Sens. 1 (100%)
Acute toxicity - category 4
Skin sensitization - Category 1
Carcinogenicity - Category 1B
Acute Tox. 4 *
Chemistry & industry
Uses & manufacturing
Uses
Used as an agricultural fungicide; [Merck Index]
Farming (Pesticides) [Category: Industry]
Applications
UsesAgricultural fungicide.
UsesPesticides and plant growth
UsesPropineb is a dithiocarbamate compound, which is used as a fungicide. Sensitization was reported in an agricultural worker.
Additional notes
DefinitionChEBI: A polymeric complex of zinc with the propylene 1,2-bis(dithiocarbamate) anionic ligand. A fungicide, it is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grape , tomatoes, potatoes, berries, citrus, rice and tea.
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…