Basic information
- CAS
2385-81-1- Standard SMILES
CCOC(=O)C1(c2ccccc2)CCN(CCOCC2CCCO2)CC1- InChIKey
NNCOZXNZFLUYGG-UHFFFAOYSA-N- Molecular formula
- C21H31NO4
- Average molar mass
- 361.5 g/mol
- Monoisotopic mass
- 361.22530847
Overview
Furethidine is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse. It is a Opiates substance.
Names & identifiers
- Preferred name
- Furethidine
- IUPAC
- ethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
- English name
- furethidine
- Molecular formula
- C21H31NO4
- Molecular weight
- 361.48
Names & synonyms
FURETHIDINEFurethidinumFuretidinaFuretidina [DCIT]2385-81-1Furethidinum [INN-Latin]Furethidine [INN:BAN:DCF]EINECS 219-195-06U9XA4JOD4BRN 0496786IDS-NF-002Ethyl 4-phenyl-1-(2-tetrahydrofurfuryloxyethyl)piperidine-4-carboxylate
Show more names
NNCOZXNZFLUYGG-UHFFFAOYSA-N4-phenyl-1-[2-(tetrahydrofurfuryloxy)ethyl]isonipecot ethyl esterethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenyl-piperidine-4-carboxylate4-Phenyl-1-[2-[(tetrahydrofuran-2-yl)methoxy]ethyl]-4-piperidinecarboxylic acid ethyl ester4-Piperidinecarboxylic acid, 4-phenyl-1-[2-[(tetrahydro-2-furanyl)methoxy]ethyl]-, ethyl ester
FURETHIDINE [MI]FURETHIDINE [INN]FURETHIDINE [WHO-DD]1-(2-Tetrahydrofurfuryloxyethyl)-4-phenylpiperidine-4-carboxylic acid ethyl esterethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylateFurethidine (INN)Furethidinum (INN-Latin)Isonipecotic acid, 4-phenyl-1-(2-((tetrahydrofurfuryl)oxy)ethyl)-, ethyl ester
Database identifiers
Properties
Computed structural properties
- XLogP
- 2.7
- Topological polar surface area
- 48 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 9
- Heavy atoms
- 26
- Formal charge
- 0
- Complexity
- 428
Experimental & physicochemical properties
Drugs
DEA NFLIS-Drug Category -> Narcotic Analgesics
DEA Schedule I Controlled Substance -> Opiates
Dissociation Constants7.48
Physicochemical properties
- Melting point
- 28 ° · ~28°
- Boiling point
- 0.5 · bp0.5 210°; bp0.3 175-183°
- Density
- 1.138 · 1.1380 (rough estimate)
- refractive index
- 20 · nD20 1.5219
- pka
- 7.48 · 7.48(at 25℃)
- FDA UNII
- 6 U9XA4JOD4 · 6U9XA4JOD4
- DEA Controlled Substances
- 9626 CSA · CSCN: 9626CSA SCH: Schedule INARC: Yes
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory InformationDEA schedule I controlled substance
Safety data
- DEA Controlled Substances
- CSCN: 9626CSA SCH: Schedule INARC: Yes
Chemistry & industry
Applications
UsesFurethidine is an opioid derivative which has effects of analgesia, sedation and nausea. It is currently not used as a medication.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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