Basic information
- Standard SMILES
O.O.O.O.O.O.O.O.O.O.O.O.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+]- InChIKey
ASTWEMOBIXQPPV-UHFFFAOYSA-K- Molecular formula
- H24Na3O16P
- Average molar mass
- 380.12 g/mol
- Monoisotopic mass
- 380.04950452
Names & identifiers
- Preferred name
- Trisodium phosphate dodecahydrate
- IUPAC
- trisodium;phosphate;dodecahydrate
- English name
- Sodium phosphate tribasic dodecahydrate
- Molecular formula
- H6NaO5P
- Molecular weight
- 140.01
Names & synonyms
Show more names
Database identifiers
- CAS
10101-89-0- PubChem CID
- 61473
- DTXSID
DTXSID0049810- UNII
- B70850QPHR
- EC Number
- 600-151-8
Properties
Computed structural properties
- Topological polar surface area
- 98.3 Ų
- Hydrogen bond donors
- 12
- Hydrogen bond acceptors
- 16
- Rotatable bonds
- 0
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 36
Experimental & physicochemical properties
Physical Description
Liquid; Dry Powder
Colorless to white crystals; [CAMEO]
Physicochemical properties
- Melting point
- 75 °C · 75 °C
- Density
- 1.62 g/mL · 1.62 g/mL at 25 °C
- bulk density
- 950 kg/m3 · 950kg/m3
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- solubility
- 2 O: · H2O: 0.5 M at 20 °C, clear, colorless
- form
- Solid
- Specific Gravity
- 1.62 · 1.62
- color
- White
- PH Range
- 13 at · 13 at 190 g/l at 25 °C
- PH
- 12 · 12 (10g/l, H2O, 20℃)
- Water Solubility
- 258 g/L · 258 g/L (20 ºC)
- Merck
- 14 · 14,8662
- Stability
- Stable. Incompatible with strong acids. Keep dry.
- InChI
- 1S/3Na.H3O4P.12H2O/c;;;1-5(2,3)4;;;;;;;;;;;;/h;;;(H3,1,2,3,4);12*1H2/q3*+1;;;;;;;;;;;;;/p-3
- InChIKey
- ASTWEMOBIXQPPV-UHFFFAOYSA-K
- SMILES
- O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O
- LogP
- -2.148 · -2.148 (est)
- CAS DataBase Reference
- 10101 · 10101-89-0(CAS DataBase Reference)
- FDA UNII
- 70850 QPHR · B70850QPHR
- EPA Substance Registry System
- Trisodium phosphate dodecahydrate (10101-89-0)
- Absorption
- 0.023 at · ≤0.023 at 280 in H2O at 0.5M≤0.035 at 260 in H2O at 0.5M
- UNSPSC Code
- 12352302 · 12352302
- NACRES
- 24 · NB.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P264-P271-P280-P302+P352-P305+P351+P338
- target organs
- Respiratory system
- Hazard Codes
- C
- Risk Statements
- 34 · 34-35-36/38
- Safety Statements
- 26 · 26-36/37/39-45-24/25
- RIDADR
- 3262 · UN 3262 8/PG 3
- WGK Germany
- 1 · 1
- RTECS
- 9575000 · TC9575000
- TSCA
- Yes
- HazardClass
- 8 · 8
- PackingGroup
- III
- HS Code
- 28352300 · 28352300
- Storage Class
- 8 A · 8A - Combustible corrosive hazardous materials
- Hazard Classifications
- 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Toxicity
- 50 orally · LD50 orally in Rabbit: 7400 mg/kg
- Limited Quantities
- 5 kg · 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 1.3% (6 of 472) of reports.
Danger
H314 (20.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H315 (74.6%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (77.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (44.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 472 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 6 of 472 reports by companies.;There are 16 notifications provided by 466 of 472 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Regulatory Information
Chemical: Phosphoric acid, trisodium salt, dodecahydrate
Phosphoric acid, trisodium salt, dodecahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, trisodium salt, dodecahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Trisodium phosphate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Skin Corr. 1C (20.8%);Skin Irrit. 2 (74.6%);Eye Irrit. 2 (77.8%);STOT SE 3 (44.9%)
Skin corrosion - category 1B
Toxicology
Regulatory information
Regulatory Information
Chemical: Phosphoric acid, trisodium salt, dodecahydrate
Phosphoric acid, trisodium salt, dodecahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, trisodium salt, dodecahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Trisodium phosphate: Does not have an individual approval but may be used under an appropriate group standard
Safety data
- wgk
- 1
- tsca
- Yes
- rtecs
- TC9575000
- ridadr
- UN 3262 8/PG 3
- hs_code
- 28352300
- Toxicity
- LD50 orally in Rabbit: 7400 mg/kg
- risk_code
- 34-35-36/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- C
- safety_code
- 26-36/37/39-45-24/25
- hazard_class
- 8
- Storage Class
- 8A - Combustible corrosive hazardous materials
- packing_group
- III
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Limited Quantities
- 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Uses & manufacturing
Uses
Used to develop photos, clarify sugar, remove boiler scale, soften water, manufacture paper, tan leather, and make detergents; [HSDB] Used in food to increase alkalinity; [CHEMINFO]
Pulp and Paper Processing [Category: Industry];Leather Tanning and Processing [Category: Industry];Photographic Processing [Category: Other]
Applications
Uses(1) It can be used as the water softener, detergent, boiler detergents, metal rust inhibitors, dyeing fixing agent, fluxing agent for enamel production, bleaching agent, leather degreaser agent and degumming agent etc. (2) It can be used as analytical reagents, water softener and metal cleaning agent. (3) It can be used as water softener, boiler cleaning agents and metal rust inhibitors. It can also be applied to paper, leather, photography and so on. (4) It can be used as the softener, detergent, boiler scale inhibitor, water softener for paper dyeing water softener, PH buffers of the adhesive for producing glossy paper, the fixing agent for textile printing, mercerized enhancer for fabric, tendering resistant agent for making thread in the chemical, textile printing paper dyeing, power generation and other industries. It can be used for chemical degreasing and decontamination, and can also be used as the metal corrosion resistance agent or rust inhibitor in metallurgical industry; fluxing agent and bleaching agent in enamel industry; degreasing agents and rawhide unglued agent in leather industry; favorable promoter for photographic developing solution; tooth cleaners and detergents for bottle; coagulating agent for rubber latex; juice purification agents. (5) It can be used as water softener, photographic developer and detergents. (6) Phosphate has the effect of improving quality in food processing, for example, keep the water capacity in meat and improve adhesive force in order to reduce the loss of nutrients make the meat soft. It can be used as the emulsifier, nutritional supplement and quality improver In food processing. It is the raw material of making the buck. It can also be used for refining the sugar and making theα-starch. The detergents for the bottles and cans.
DescriptionSodium phosphate tribasic dodecahydrate is also known as trisodium phospate or TSP. It is a highly soluble in water and widely used as a cleaning agent. The pH of a 1% solution is typically around 12, making this reagent sufficiently alkaline for saponification of grease and oils. In combination with surfactants, TSP is an excellent agent for cleaning everything from laundry to concrete driveways. This versatility and low manufacturing price made TSP the basis for a plethora of cleaning products sold in the mid-20th century. Trisodium phosphate is used in the isolation of mycobacteria, including culturing of tubercle bacilli. Has been used as a protein precipitant in certain applications and in co-precipitation and fractionization of nucleotides. May be used for the preservation of biologically active soil samples. Because of the alkaline pH, TSP disrupts cytoplasmic and outer membranes of Salmonella enterica cells making it useful in preventing the spread of bacteria. It is used in photographic developing, clarifying sugar, removing boiler scale, softening water and manufacturing of paper. They are added to many foods as an emulsifier to prevent oil separation. It can be utilized as a leavening agent. Some instances of these foods include the batter coating on breaded fish or chicken, and commercially baked cakes. Adding this item to food increases the shelf life of the food, maintaining the texture and visual aspect of the food.
UsesSodium phosphate tribasic dodecahydrate is often used in the formulation of various buffers.
General DescriptionSodium phosphate tribasic dodecahydrate is a hydrated trisodium salt of phosphoric acid. It is widely used in various water treatment methods.
Upstream & downstream products
Upstream raw materials
Downstream products
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