Basic information
- CAS
64-99-3- Standard SMILES
CCn1cnc(C(=O)NC)c1C(=O)NC- InChIKey
RYRFAMRQBZNEPX-UHFFFAOYSA-N- Molecular formula
- C9H14N4O2
- Average molar mass
- 210.23 g/mol
- Monoisotopic mass
- 210.1116757
Overview
A xanthine-related, putative nootropic drug.
Names & identifiers
- Preferred name
- Ethimizol
- IUPAC
- 1-ethyl-4-N,5-N-dimethylimidazole-4,5-dicarboxamide
- English name
- Etimizol
- Molecular formula
- C9H14N4O2
- Molecular weight
- 210.23
Names & synonyms
ETIMIZOL64-99-3EthimizolEthimizoleEthymisoleEthylnorantifeineNG2MF3646PDTXSID302139841H-Imidazole-4,5-dicarboxamide, 1-ethyl-N,N'-dimethyl-EthymizolAethimizoleRefChem:139241
Show more names
EthymisolEtimizol, 99.5%Ethylnorantifein
DTXCID60136475AntiffineEtimizole1-ethyl-4-N,5-N-dimethylimidazole-4,5-dicarboxamide1-ethyl-N4,N5-dimethyl-1H-imidazole-4,5-dicarboxamide1-Ethyl-4-N,5-N-dimethyl-1H-imidazole-4,5-dicarboxamide1-ethyl-N,N'-dimethyl-1H-imidazole-4,5-dicarboxamideEthimizole;Ethymisol;Ethymisole
Database identifiers
- CAS
64-99-3- PubChem CID
- 6168
- DTXSID
DTXSID30213984- ChEMBL
CHEMBL4303294- UNII
- NG2MF3646P
- Nikkaji
- J21.209A
Properties
Computed structural properties
- XLogP
- -0.5
- Topological polar surface area
- 76 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 256
Physicochemical properties
- Melting point
- 143 · 143-144℃
- Boiling point
- 563.4 · 563.4±35.0 °C(Predicted)
- Density
- 1.26 · 1.26±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 33.33 mg/mL · Ethanol: ≥ 33.33 mg/mL (158.54 mM)
- form
- Solid
- pka
- 14.22 · 14.22±0.46(Predicted)
- color
- White to off-white
- FDA UNII
- 2 MF3646P · NG2MF3646P
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationDrugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
Applications
UsesEtimizol(Ethymisole; Antiffine; Ethylnorantifein) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). Etimizol can decrease the K-+ permeability of neurons' membrane during action potential.
Suppliers25 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Aladdin Scientific[email protected]
United Life Science020-82099279 18988968278 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
AdooQ BioScience, LLC+1 (866) 930-6790 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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