Basic information
- CAS
53581-53-6- Standard SMILES
Br.COc1cc(CC(C)N)c(OC)cc1Br- InChIKey
KOUBEZAODVTFTG-UHFFFAOYSA-N- Molecular formula
- C11H17Br2NO2
- Average molar mass
- 355.07 g/mol
- Monoisotopic mass
- 352.9626
Names & identifiers
- Preferred name
- 2,5-Dimethoxy-4-bromoamphetamine, monohydrobromide, (+-)-
- IUPAC
- 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine;hydrobromide
- English name
- (+/-)-2,5-DIMETHOXY-4-BROMO-AMPHETAMINE HYDROBROMIDE
- Molecular formula
- C11H17Br2NO2
- Molecular weight
- 355.07
Names & synonyms
RefChem:1214902,5-Dimethoxy-4-bromoamphetamine, monohydrobromide, (+-)-Brolamfetamine hydrobromide53581-53-6DTXSID70490011-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine;hydrobromide1S6K9S6785DL-4-Bromo-2,5-dimethoxyamphetamine hydrobromideNCGC00168267-01UNII-1S6K9S6785dl-2,5-Dimethoxy-4-bromoamphetamine hydrobromideDOB HYDROBROMIDE
Show more names
dobDO betaBrolamfetamine HBr[+/-]-DOB HYDROBROMIDEKOUBEZAODVTFTG-UHFFFAOYSA-N4-bromo-2,5-dimethoxyamphetamine hydrobromidedl-2,5-dimethoxy-4-bromoamphetaminehydrobromidedl-4-bromo-2,5-dimethoxyamphetaminehydrobromide(+-)-2,5-dimethoxy-4-bromoamphetamine*hydrobromid(+/-)-2,5-DIMETHOXY-4-BROMO-AMPHETAMINE HYDROBROMIDE
DOB,BENZYLOXY-DL-4-Bromo-2,5-dimethoxy-alpha-methylphenethylamine hydrobromidePhenethylamine, 4-bromo-2,5-dimethoxy-alpha-methyl-, hydrobromide, DL-orb2815439SCHEMBL6429990CHEMBL2355922DTXCID8028927SCHEMBL31545259
Database identifiers
- CAS
53581-53-6- PubChem CID
- 62064
- DTXSID
DTXSID7049001- ChEMBL
CHEMBL2355922- UNII
- 1S6K9S6785
- EC Number
- 637-315-3
Properties
Computed structural properties
- Topological polar surface area
- 44.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 4
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 191
Physicochemical properties
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 1 S6K9S6785 · 1S6K9S6785
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
- Hazard statements
- 302 · H302-H310-H330
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
- Hazard Codes
- T+
- Risk Statements
- 26 · 26/27/28
- Safety Statements
- 28 · 28-36/37-45
- RIDADR
- 2811 · UN 2811 6.1/PG 2
- WGK Germany
- 3 · 3
- RTECS
- 300000 · SH0300000
- HazardClass
- 6.1 · 6.1(a)
- PackingGroup
- I
- Toxicity
- 5 · A hallucinogenic (psychedelic) agent that is obtained by chemical synthesis. It may catalyze severe emotional problems or psychosis in predisposed individuals, and in large doses, produces peripheral arterial spasm which, if not treated, can lead to gangrene. DOB is a potent serotonin 5-HT2 agonist, and although the underlying mechanism of action for hallucinogens is not well understood, this may be related to its actions in the CNS. Symptoms include hyperreflexia, restlessness, perceptual alterations, and illusions, including changes in touch, taste, and odor, and the thinking process is substantially altered. At high doses, it causes hallucinations, loss of contact with reality, and pain and coldness in the extremities at toxic levels. Therapeutically, peripheral arterial spasm has been treated with intraarterial tolazoline hydrochloride. Its LD50 is in mice 80 mg/kg, i.v., in rats 8 mg/kg, i.p., in dogs 4 mg/kg. i.v., and in monkeys 2 mg/kg, i.v.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P260, P262, P264, P270, P271, P280, P284, P301+P317, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- wgk
- 3
- rtecs
- SH0300000
- ridadr
- UN 2811 6.1/PG 2
- Toxicity
- A hallucinogenic (psychedelic) agent that is obtained by chemical synthesis. It may catalyze severe emotional problems or psychosis in predisposed individuals, and in large doses, produces peripheral arterial spasm which, if not treated, can lead to gangrene. DOB is a potent serotonin 5-HT2 agonist, and although the underlying mechanism of action for hallucinogens is not well understood, this may be related to its actions in the CNS. Symptoms include hyperreflexia, restlessness, perceptual alterations, and illusions, including changes in touch, taste, and odor, and the thinking process is substantially altered. At high doses, it causes hallucinations, loss of contact with reality, and pain and coldness in the extremities at toxic levels. Therapeutically, peripheral arterial spasm has been treated with intraarterial tolazoline hydrochloride. Its LD50 is in mice 80 mg/kg, i.v., in rats 8 mg/kg, i.p., in dogs 4 mg/kg. i.v., and in monkeys 2 mg/kg, i.v.
- risk_code
- 26/27/28
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- T+
- safety_code
- 28-36/37-45
- hazard_class
- 6.1(a)
- packing_group
- I
- Hazard statements
- H302-H310-H330
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.
Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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