Basic information
- CAS
69-27-2- Standard SMILES
C[N+](C)(C)CC[N+]1(C)Cc2c(Cl)c(Cl)c(Cl)c(Cl)c2C1.[Cl-].[Cl-]- InChIKey
DXXUGBPKQDTBQW-UHFFFAOYSA-L- Molecular formula
- C14H20Cl6N2
- Average molar mass
- 429 g/mol
- Monoisotopic mass
- 425.975765
Names & identifiers
- Preferred name
- Chlorisondamine Chloride
- IUPAC
- trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,3-dihydroisoindol-2-ium-2-yl)ethyl]azanium dichloride
- English name
- Chlorisondamine diiodide
- Molecular formula
- C14H20Cl4N2.2Cl
- Molecular weight
- 611.94
Names & synonyms
Chlorisondamine chloride69-27-2DTXSID7046332Cloruro de clorisondaminaChlorure de chlorisondamineChlorisondamini chloridum7B58W7756GCHLORISONDAMONE CHLORIDEDTXCID5026332Isoindolinium, 4,5,6,7-tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)-, dichloride1H-Isoindolium, 4,5,6,7-tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-, dichlorideChloride, Chlorisondamine
Show more names
chlorisondamineecolidrSU-3088HisindamonhisindamoneaecolidchloridechlorisondaminechlorideChlorisondamine diiodidechlorisondaminedimethochloride
Chlorisondamine DichlorideRefChem:125334Dichloride, Chlorisondamine4,5,6,7-Tetrachloro-2-(2-dimethylaminoethyl)-2-methylisoindolinum chloride methochloridetrimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,3-dihydroisoindol-2-ium-2-yl)ethyl]azanium;dichlorideEcolidEcolid chlorideHisindamone A
Properties
Computed structural properties
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 3
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 336
Physicochemical properties
- Melting point
- 258 · 258-265° (dec)
- Boiling point
- 579.33 °C · 579.33°C (rough estimate)
- Density
- 1.4157 · 1.4157 (rough estimate)
- refractive index
- 1.6 · 1.6000 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: ~3.75 mg/mL
- form
- solid
- color
- white
- FDA UNII
- 7 B58W7756G · 7B58W7756G
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
- Hazard Codes
- Xn,N
- Risk Statements
- 22 · 22-50
- Safety Statements
- 60 · 60-61
- WGK Germany
- 2 · 2
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- wgk
- 2
- risk_code
- 22-50
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn,N
- safety_code
- 60-61
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
Applications
UsesChlorisondamine Diiodide is being used as an intracranial injection to study the localization and analysis of small drug molecules in rat brain tissue.
UsesBiochemical probe in nicotinic receptor studies.
Upstream & downstream products
Upstream raw materials
Suppliers6 total
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
陕西缔都医药化工有限公司+86-29-87569262 +86-15003564040 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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