Basic information
- CAS
7701-62-4- Standard SMILES
C[N+](C)(C)CC[N+]1(C)Cc2c(Cl)c(Cl)c(Cl)c(Cl)c2C1- InChIKey
IXWDUZLHWJKVPX-UHFFFAOYSA-N- Molecular formula
- C14H20Cl4N2+2
- Average molar mass
- 358.1 g/mol
- Monoisotopic mass
- 356.038059
Overview
Chlorisondamine is a member of isoindoles.
Names & identifiers
- Preferred name
- 4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-1H-isoindolium
- IUPAC
- trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,3-dihydroisoindol-2-ium-2-yl)ethyl]azanium
- English name
- Chlorisondamine
- Molecular formula
- C14H20Cl4N2+2
- Molecular weight
- 358.134
Names & synonyms
ChlorisondamineChlorisondamine ionChlorisondamine cation7701-62-4JD3M24F66IDTXSID0048395Isoindolinium, 4,5,6,7-tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)-RefChem:575656DTXCID10283684,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-1H-isoindoliumNCGC00163230-01UNII-JD3M24F66I
Show more names
chlorisondamine-diiodideTocris-10014,5,6,7-Tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)isoindoliniumCHEMBL1398654CHLORISONDAMINE [WHO-DD]SCHEMBL14340042BDBM84948CHEBI:135514
Database identifiers
- CAS
7701-62-4- PubChem CID
- 6244
- DTXSID
DTXSID0048395- ChEMBL
CHEMBL1398654- ChEBI
CHEBI:135514- UNII
- JD3M24F66I
- Nikkaji
- J246.997I
Properties
Computed structural properties
- XLogP
- 3.9
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 2
- Complexity
- 336
Physicochemical properties
- FDA UNII
- 3 M24F66I · JD3M24F66I
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
Additional notes
DefinitionChEBI: Chlorisondamine is a member of isoindoles.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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