Diethoxy(methyl)(3-(oxiran-2-ylmethoxy)propyl)silane
GPTMS · (3-GLYCIDYLOXYPROPYL)METHYLDIETHOXYSILANE · DIETHOXY(3-GLYCIDYLOXYPROPYL)METHYLSILANE · 3-(2,3-Epoxypropyloxy)propylMethyldiethoxysilane · KH-78 · diethoxysiL · ycidoxypropyL · (3-Glycidoxypropyl)methyldiethoxysil
Identifiers & Physical Properties
| CAS No. | 2897-60-1 |
|---|---|
| Molecular formula | C11H24O4Si |
| Average molar mass | 248.39 g/mol |
| Monoisotopic mass | 248.14438578 g/mol |
| SMILES | CCO[Si](C)(CCCOCC1CO1)OCC |
| InChIKey | OTARVPUIYXHRRB-UHFFFAOYSA-N |
| PubChem CID | 62467 |
| ChEMBL | CHEMBL3182993 |
| EC No. | 220-780-8 |
| DTXSID | DTXSID2044638 |
Chemical & Physical Properties
| Topological polar surface area | 40.2 |
|---|---|
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 4 |
| Rotatable bonds | 10 |
| Heavy atoms | 16 |
| Formal charge | 0 |
| Complexity | 183 |
| Physical Description | Liquid |
| Melting point | <0°C |
| Boiling point | 122-126 °C5 mm Hg(lit.) |
| Density | 0.978 g/mL at 25 °C(lit.) |
| Vapor pressure | 0-7910Pa at 25℃ |
| Refractive index | n20/D 1.431(lit.) |
| Flash point | >230 °F |
| Storage conditions | 2-8°C |
| Physical state | liquid |
| Color | Colorless to Almost colorless |
| Specific gravity | 0.978 |
| Solubility | 1.2-1000g/L at 20℃ |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 121965 |
| InChI | 1S/C11H24O4Si/c1-4-14-16(3,15-5-2)8-6-7-12-9-11-10-13-11/h11H,4-10H2,1-3H3 |
| InChIKey | OTARVPUIYXHRRB-UHFFFAOYSA-N |
| SMILES | CCO[Si](C)(CCCOCC1CO1)OCC |
| LogP (partition coefficient) | -0.7-2.7 at 20℃ |
| CAS DataBase Reference | 2897-60-1(CAS DataBase Reference) |
| FDA UNII | H04254P08T |
| EPA Substance Registry System | 3-(Methyldiethoxysilyl)propyl glycidyl ether (2897-60-1) |
| UNSPSC Code | 12352103 |
| NACRES | NA.23 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Target organs | Respiratory system |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard symbols | Xi |
| Risk statements (R) | 36/37/38-41 |
| Safety statements (S) | 26-36/39 |
| Water hazard class (WGK) | 3 |
| F | 10-21 |
| TSCA inventory status | TSCA listed |
| Customs code | 29319090 |
| Storage class | 10 - Combustible liquids |
| Hazard class | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| REACH registrations | Active |
Safety & Regulations
| GHS classification | WarningH315 (62.5%): Causes skin irritation [Warning Skin corrosion/irritation]P203, P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 773 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatory information | Chemical: Silane, diethoxymethyl [3-(oxiranylmethoxy) propyl]-Oxirane, 2-[[3-(diethoxymethylsilyl)propoxy]methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[[3-(diethoxymethylsilyl)propoxy]methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.Status: Active Update: 06-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/17529[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Hazard Classes and Categories | Skin Irrit. 2 (62.5%) |
| F | 10-21 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| Customs code | 29319090 |
| Risk statements (R) | 36/37/38-41 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
Applications & Uses
Uses
(3-Glycidyloxypropyl)methyldiethoxysilane is an organo-functional silane that can be used as a coupling agent between inorganic fillers (powdered silicas, glass, fiberglass, ceramics, etc.) and a wide variety of polymers such as epoxy, melamine, phenolic and urethane resins, polystyrene plastic, acrylic sealants, butyl rubber and water soluble polymers that contain hydroxyl groups and/or primary or secondary amine groups.
Uses
3-(Glycidoxypropyl)methyldiethoxysilane, silane coupling agent KH-7180, is a versatile epoxy organo-reactive silane with two hydrolyzable ethoxy groups. It provides shelf stable non-yellowing adhesion promoter performance while enhancing physical properties in latexes and waterborne adhesive and sealant systems.
Uses
GPMS can be used in the surface modification of a variety of particles such as cellulose nanocrystals, silica nanomaterials and other silicon based substrates. It functionalizes these surfaces by attaching the epoxy-silane groups with the surface molecules.
General Description
Diethoxy(3-glycidyloxypropyl)methylsilane (GPMS) is an epoxysilane which can be used as a silane coupling agent for the surface treatment of a variety of materials. These silanes can also be used as adhesion promoters by modifying the surface properties of the substrates and elastomeric materials.