Basic information
- CAS
3187-52-8- Standard SMILES
COc1ccc2c(c1)OCC1(O)c3ccc(OC)cc3OC21- InChIKey
VVPGAJNPGZZNBM-UHFFFAOYSA-N- Molecular formula
- C17H16O5
- Average molar mass
- 300.3 g/mol
- Monoisotopic mass
- 300.09977361
Overview
CID 44428627 has been reported in Ononis viscosa and Sophora flavescens with data available.
Names & identifiers
- Preferred name
- (6aS,11aS)-3,9-dimethoxy-6,11a-dihydro-[1]benzofuro[3,2-c]chromen-6a-ol
- IUPAC
- 3,9-dimethoxy-6,11a-dihydro-[1]benzofuro[3,2-c]chromen-6a-ol
- English name
- variabilin
- Molecular formula
- C17H16O5
- Molecular weight
- 300.31
Names & synonyms
Variabilin?(6aS,11aS)-3,9-dimethoxy-6,11a-dihydro-[1]benzofuro[3,2-c]chromen-6a-olCID 44428627orb1991670SCHEMBL13743175VVPGAJNPGZZNBM-UHFFFAOYSA-NAKOS040735078T125054B0005-4583013,9-Dimethoxy-6H-[1]benzofuro[3,2-c]chromen-6a(11ah)-ol #6H-Benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol, 3,9-dimethoxy-, (6aR-cis)-variabilin
Show more names
Homopisatin(+)-HomopisatinVariabilin(Dalbergia)(6aR)-3,9-Dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-6aβ(11aβH)-ol6H-Benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol, 3,9-dimethoxy-, (6aR,11aR)-
Database identifiers
- CAS
3187-52-8- PubChem CID
- 627142
- Nikkaji
- J2.916.777J
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 57.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 416
Chemistry & industry
Pharmacology
Cellular LocationsMembrane
Applications
UsesVariabilin (Homopisatin) is a potent RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. Variabilin potently inhibits platelet aggregation induced by the platelet agonists ADP, collagen, and thrombin receptor peptide SFLLRNP. Variabilin also blocks platelet adhesion to immobilized Fg. In addition, Variabilin inhibits binding of purified human GPIIb-IIIa to immobilized Fg[1][2].
Suppliers2 total
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Additional notes
DefinitionChEBI: (-)-Variabilin is a member of pterocarpans.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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