Basic information
- CAS
5704-60-9- Standard SMILES
CC(C)NCC(O)c1ccc([N+](=O)[O-])cc1.Cl- InChIKey
STGOXRVTUNXXLQ-UHFFFAOYSA-N- Molecular formula
- C11H17ClN2O3
- Average molar mass
- 260.72 g/mol
- Monoisotopic mass
- 260.0927701
Names & identifiers
- Preferred name
- Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-4-nitro-, monohydrochloride
- IUPAC
- 1-(4-nitrophenyl)-2-(propan-2-ylamino)ethanol;hydrochloride
- English name
- (±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride
- Molecular formula
- C11H16N2O3.ClH
- Molecular weight
- 260.72
Names & synonyms
Nifenalol hydrochloride5704-60-9Nifenalol HClINPEA2KMT7J8EZCRefChem:1078539Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-4-nitro-, monohydrochloride227-194-11-(4-Nitrophenyl)-1-hydroxy-2-isopropylaminoethane hydrochlorideNifenalol (hydrochloride)2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride74-10-2
Show more names
Nifenalol monohydrochloridenifenalol.HCl, 10 mM in DMSO()-alpha-[[isopropylamino]methyl]-4-nitrobenzylalcoholmonohydrochloride(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochloride(±)-alpha-[[isopropylamino]methyl]-4-nitrobenzyl alcohol monohydrochlorideBenzenemethanol, α-[[(1-methylethyl)amino]methyl]-4-nitro-, monohydrochloride
1-(4-nitrophenyl)-2-(propan-2-ylamino)ethanol;hydrochlorideisophenethanol(+-)-2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride5704-60-9 (HCl)nifenalol.HClNifenalol?UNII-2KMT7J8EZCINPEA HYDROCHLORIDE
Properties
Computed structural properties
- Topological polar surface area
- 78.1 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 220
Physicochemical properties
- Melting point
- 181 ° · 181°
- storage temp.
- -20 °C · -20°C
- solubility
- 30 mg/ml,DMSO: · DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- FDA UNII
- 2 KMT7J8EZC · 2KMT7J8EZC
Chemistry & industry
Applications
UsesNifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure[1].
Suppliers29 total
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
Aladdin Scientific[email protected]
InvivoChem中国13549236410 · [email protected]
学研惠（武汉）科技有限公司15727060112 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
Related reactions
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Compound notes
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