CP-10447
Basic information
- CAS
843-93-6- Standard SMILES
Cc1cc(Br)ccc1-n1c(C)nc2ccccc2c1=O- InChIKey
CIYGULLCDQXZNK-UHFFFAOYSA-N- Molecular formula
- C16H13BrN2O
- Average molar mass
- 329.19 g/mol
- Monoisotopic mass
- 328.02113
Names & identifiers
- Preferred name
- CP-10447
- IUPAC
- 3-(4-bromo-2-methylphenyl)-2-methylquinazolin-4-one
- English name
- CP-10447
- Molecular formula
- C16H13BrN2O
- Molecular weight
- 329.19
Names & synonyms
CP-10447RefChem:579352663-563-7843-93-63-(4-bromo-2-methylphenyl)-2-methylquinazolin-4-oneCP 104473-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinoneorb17408923-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone3-(4-bromo-2-methylphenyl)-2-methylquinazolin-4(3h)-oneDTXSID70275687FC20579
Show more names
4(3H)-Quinazolinone, 3-(4-bromo-2-methylphenyl)-2-methyl-
CP-10447, >=98% (HPLC)T685884(3H)-Quinazolinone, 3-(4-bromo-2-methylphenyl)-2-methyl-; 4(3H)-Quinazolinone, 3-(4-bromo-o-tolyl)-2-methyl- (6CI,7CI,8CI); CP 10447; CP-10447
Database identifiers
- CAS
843-93-6- PubChem CID
- 63773
- DTXSID
DTXSID70275687- EC Number
- 663-563-7
- Nikkaji
- J757.333B
Properties
Computed structural properties
- XLogP
- 3.2
- Topological polar surface area
- 32.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 423
Physicochemical properties
- Melting point
- 148 · 148-150°C
- storage temp.
- Refrigerator
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
- Hazard statements
- 301 · H301
- Precautionary statements
- 264 · P264-P270-P301+P310-P321-P330-P405-P501
- Hazard Codes
- T
- Risk Statements
- 25 · 25
- Safety Statements
- 45 · 45
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Safety data
- risk_code
- 25
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- T
- safety_code
- 45
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
Chemistry & industry
Applications
UsesCP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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