Chlorotrifluoromethane

Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep cylinder cool by spraying with water.

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

ON FROSTBITE: rinse with plenty of water, do NOT remove clothes.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Do not touch or walk through spilled material.

INHALATION: Remove to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen.

General First Aid:

· Wear positive pressure self-contained breathing apparatus (SCBA).

1000.0 [ppm]

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.

SUFFICIENT EXHAUST & GENERAL VENTILATION SHOULD BE PROVIDED TO KEEP VAPOR CONCN BELOW RECOMMENDED LEVELS. /FLUOROCARBONS/

If material not involved in fire: Attempt to stop leak if without undue personnel hazard.

Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment.

Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:

Immediate precautionary measure

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 188(SRC), determined from a measured log Kow of 1.65(2) and a recommended regression-derived equation(3), indicates that chlorotrifluoromethane is expected to have moderate mobility in soil(SRC). Volatilization of chlorotrifluoromethane is expected from moist soil surfaces(SRC) given a measured Henry's Law constant of 1.38 atm-cu m/mole(4). Chlorotrifluoromethane is expected to volatilize rapidly from dry soil surfaces based on a vapor pressure of 2.14X10+4 mm Hg(SRC) at 25 °C(5). Highly chlorinated/fluorinated compounds are not expected to biodegrade rapidly(6).

AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 188(SRC), determined from a measured log Kow of 1.65(2) and a recommended regression-derived equation(3), indicates that chlorotrifluoromethane is not expected to adsorb to suspended solids and sediment in water(SRC). Chlorotrifluoromethane is expected to volatilize rapidly from water surfaces(3) based on a measured Henry's Law constant of 1.38 atm-cu m/mole(4). Estimated half-lives for a model river and model lake are 3 and 97 hours, respectively(SRC). According to a classification scheme(5), an estimated BCF value of 10(3,SRC), from the measured log Kow(2), suggests that bioconcentration in aquatic organisms is low(SRC). Highly chlorinated/fluorinated compounds are not expected to biodegrade rapidly(6).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), chlorotrifluoromethane, which has a measured vapor pressure of 2.14X10+4 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase chlorotrifluoromethane is slowly degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 62 years(3,SRC). This compound will gradually diffuse into the stratosphere above the ozone layer where it will slowly degrade due to direct photolysis from UV-C radiation and contribute to the catalytic removal of stratospheric ozone(4,SRC). The half-life for this reaction has been estimated to range from 180 to 450 years(4).

Confusion. Dizziness. Headache. Unconsciousness.

ON CONTACT WITH LIQUID: FROSTBITE.

See Skin.

The Koc of chlorotrifluoromethane is estimated as approximately 188(SRC), using a measured log Kow of 1.65(1) and a regression-derived equation(2). According to a recommended classification scheme(3), this estimated Koc value suggests that chlorotrifluoromethane is expected to have moderate mobility in soil(SRC).

Chlorotrifluoromethane was detected in the troposphere above the Antarctic region at concentrations of 3.6 and 3.2 parts per trillion, with an average global concentration estimated as 4.0 parts per trillion(1). Chlorotrifluoromethane was detected at a concentrations of 3.9 parts per trillion (14.4 kilometers above the earth's surface) and 2.3 parts per trillion (33.2 kilometers above the earth's surface)(2).

Trace gases have been measured, by electron-capture gas chromatography and gas chromatography-mass spectrometry, at the South Pole (SP) in Antarctica and in the US Pacific Northwest (PNW) (aprox 45 deg N) during Jan of each year 1975-80. The concn of chlorotrifluoromethane increased at a rate of 12%/yr at the SP and 8%/yr in the PNW.

EARLY...HUMAN EXPERIENCE INDICATED THAT HIGH VAPOR CONCN (EG, 20%) MAY CAUSE CONFUSION, PULMONARY IRRITATION, TREMORS & RARELY COMA, BUT THAT THESE EFFECTS WERE GENERALLY TRANSIENT & WITHOUT LATE SEQUELAE. ...CAUSE OF DEATH /FROM ABUSE OF FLUOROCARBONS/ IS IN CONSIDERABLE DOUBT... FREEZING OF AIRWAY SOFT TISSUES CAN PROBABLY BE ELIMINATED AS A CAUSE OF DEATH EXCEPT IN CASES WHERE THE PRODUCT WAS SPRAYED DIRECTLY INTO THE MOUTH FROM ITS CONTAINER OR FROM A BALLOON CONTAINING SOME LIQUID. LARYNGEAL SPASM OR EDEMA, OXYGEN DISPLACEMENT, OR SENSITIZATION OF MYOCARDIUM ENDOGENOUS CATECHOLAMINES WITH SUBSEQUENT VENTRICULAR FIBRILLATION APPEAR TO BE REASONABLE POSSIBILITIES. /FLUOROCARBON REFRIGERANTS & PROPELLANTS/

EXCESSIVE SKIN CONTACT WITH LIQUID FLUOROCARBONS SHOULD BE MINIMIZED TO PREVENT DEFATTING OF SKIN... /FLUOROCARBONS/

A SPECIAL CLASS OF CHEMICALS SUBJECT TO ABUSE BY INHALATION ARE THE FLUOROHYDROCARBONS... THE "SNIFFING" OF SUCH AEROSOL SPRAYS IS HAZARDOUS PRACTICE. ...110 "SUDDEN SNIFFING DEATHS" /HAVE BEEN IDENTIFIED/... IN EACH CASE THE VICTIM SPRAYED THE AEROSOL INTO A PLASTIC BAG, INHALED THE CONTENTS, BECAME EXCITED, RAN 90 M OR SO, COLLAPSED, & DIED. NECROPSY FINDINGS WERE LARGELY NEGATIVE... ALTHOUGH AMOUNT OF PROPELLANT ABSORBED INTO BLOOD FROM USE OF HAIRSPRAY, COSMETIC, HOUSEHOLD, & MEDICATED AEROSOLS MUST VARY WITH CIRCUMSTANCES, PHYSICIAN IS ADVISED TO COUNSEL...PATIENT ON POTENTIAL DANGERS, PARTICULARLY FROM THEIR USE IN POORLY VENTILATED CONFINED AREAS. IT IS POSSIBLE THAT PATIENTS WITH CARDIAC OR RESPIRATORY DISORDERS MAY PROVE ESPECIALLY SUSCEPTIBLE. /FLUOROHYDROCARBONS/

BECAUSE OF DECREASED USE IN CONSUMER PRODUCTS, ABUSE HAS BEEN ELIMINATED.

For more Human Toxicity Excerpts (Complete) data for CHLOROTRIFLUOROMETHANE (7 total), please visit the HSDB record page.

An estimated BCF value of 10 was calculated for chlorotrifluoromethane(SRC), using a measured log Kow of 1.65(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).

This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Chlorotrifluoromethane is produced, as an intermediate or a final product, by process units covered under this subpart.