N-Methyl-L-proline

HCID 643474
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
475-11-6
Standard SMILES
CN1CCC[C@H]1C(=O)O
InChIKey
CWLQUGTUXBXTLF-YFKPBYRVSA-N
Molecular formula
C6H11NO2
Average molar mass
129.16 g/mol
Monoisotopic mass
129.07897859

Overview

N-methylproline is an L-proline derivative obtained by replacement of the amino hydrogen by a methyl group. It has a role as a plant metabolite and a human metabolite. It is a tertiary amino compound and a L-proline derivative. It is a tautomer of a N-methylproline zwitterion.

Names & identifiers

Preferred name
N-Methyl-L-proline
IUPAC
(2S)-1-methylpyrrolidine-2-carboxylic acid
English name
N-Methyl-L-proline
Molecular formula
C6H11NO2
Molecular weight
129.16

Names & synonyms

N-Methyl-L-proline475-11-6N-methylprolineCHEBI:90344DTXSID30349191RefChem:830531DTXCID90300263N-Methylpyrrolidine-2-carboxylic acidh-n-me-pro-ohHYGRIC ACID(2S)-1-methylpyrrolidine-2-carboxylic acid1-methyl-L-proline
Show more names
N-Me-ProN-ME-PROLINEHygrinic acidN-Me-L-Pro-OHPYRD(2)-OH H2O
N-Me-Pro-OHL-Proline, 1-methyl-(S)-1-methylpyrrolidine-2-carboxylic acidMFCD00011565methyl-l-prolineN-methyl proline(S)-1-Methyl-pyrrolidine-2-carboxylic acid(S)-methylproline

Database identifiers

CAS
475-11-6
PubChem CID
643474
DTXSID
DTXSID30349191
ChEBI
CHEBI:90344
EC Number
849-164-2
Nikkaji
J5.969B

Properties

Computed structural properties

XLogP
-1.9
Topological polar surface area
40.5 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
1
Heavy atoms
9

Physicochemical properties

Melting point
114 · 114-116 °C(lit.)
Boiling point
227 ℃ · 227℃
Density
1.153 · 1.153
Flash point
91.1 ℃ · 91.1℃
refractive index
1.5 · 1.5000
storage temp.
-20 °C · Sealed in dry,Store in freezer, under -20°C

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

Warning

H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (66.7%)

Safety data

wgk
3
Symbol(GHS)
GHS07
hazard_class
IRRITANT
Storage Class
13 - Non Combustible Solids
Hazard statements
H302-H315-H319-H332-H335
Precautionary statements
P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Chemistry & industry

Pharmacology

Tissue LocationsPlacenta

Applications

UsesN-Methyl-L-proline, is an aminoacid which is widely used in pharmaceuticals and food industry.

Upstream & downstream products

Suppliers100 total

上海康恩博医药科技有限公司17510465506 · [email protected]
苏州道澜生物医药科技有限公司15952404857 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]
上海凌富药物研究有限公司+86(21)5895 0110 19945755304 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
Additional notes · 1 item

DefinitionChEBI: N-methylproline is an L-proline derivative obtained by replacement of the amino hydrogen by a methyl group. It has a role as a plant metabolite and a human metabolite. It is a L-proline derivative and a tertiary amino compound. It is a tautomer of a N-methylproline zwitterion.

Related reactions

80 records
New reaction record

Compound notes

Loading…