N-(3-(Dimethylamino)propyl)oleamide
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Basic information
- CAS
109-28-4- Standard SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)NCCCN(C)C- InChIKey
UCWYGNTYSWIDSW-QXMHVHEDSA-N- Molecular formula
- C23H46N2O
- Average molar mass
- 366.6 g/mol
- Monoisotopic mass
- 366.3610141
Overview
The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Oleamidopropyl Dimethylamine...
Names & identifiers
- Preferred name
- N-(3-(Dimethylamino)propyl)oleamide
- IUPAC
- (Z)-N-[3-(dimethylamino)propyl]octadec-9-enamide
- English name
- N-[3-(dimethylamino)propyl]oleamide
- Molecular formula
- C23H46N2O
- Molecular weight
- 366.63
Names & synonyms
109-28-4Oleamidopropyl dimethylamineN-(3-(Dimethylamino)propyl)oleamideN-[3-(Dimethylamino)propyl]oleamideSCHERCODINE OUNIZEEN OAOleamide, N-(3-(dimethylamino)propyl)-MACKINE 50179K39JU7RNSCHERCODINE O AMIDO-AMINENSC-258347DTXSID10873803
Show more names
OleylamidopropylDimethylAminePKOON,N-DimethylolamidopropylamineN-3-Oleylamidopropyl dimethylamineOleamidopropyl Dimethylamine（PKO-O）OleamidePropylDimethylTertiaryAmineOleic acid amide propyl dimethyl tertiary amine(Z)-N-[3-(Dimethylamino)propyl]-9-octadecenamide
Oleamide, N-[3-(dimethylamino)propyl]-RefChem:856480DTXCID20912232203-661-59-Octadecenamide, N-[3-(dimethylamino)propyl]-, (9Z)-Tegamine 0-13(Z)-N-[3-(dimethylamino)propyl]octadec-9-enamideOleic acid-N,N-dimethyltrimethylenediamine condensate
Properties
Computed structural propertiesFilling in
- XLogP
- 7.4
- Topological polar surface area
- 32.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 19
- Heavy atoms
- 26
- Formal charge
- 0
- Complexity
- 326
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Oleamidopropyl Dimethylamine) -> CIR (Cosmetic Ingredient Review)
Antistatic
Physical DescriptionLiquid
Physicochemical properties
- Boiling point
- 239 ℃[at · 239℃[at 101 325 Pa]
- Density
- 0.894 · 0.894[at 20℃]
- vapor pressure
- 0 Pa · 0Pa at 20℃
- pka
- 16.29 · 16.29±0.46(Predicted)
- Water Solubility
- 1.26 g/L · 1.26g/L at 20℃
- Cosmetics Ingredients Functions
- ANTISTATIC
- Cosmetic Ingredient Review (CIR)
- 3 · N-[3-(dimethylamino)propyl]oleamide (109-28-4)
- LogP
- 1.842 at · 1.842 at 22℃
- EWG's Food Scores
- 1 · 1-4
- FDA UNII
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H314 (18.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P261, P264, P264+P265, P272, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P333+P317, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 599 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Hazard information
Regulatory Information
Chemical: 9-Octadecenamide, N-[3-(dimethylamino)propyl]-, (Z)-
9-Octadecenamide, N-[3-(dimethylamino)propyl]-, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, N-[3-(dimethylamino)propyl]-, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: N-[3-(dimethylamino)propyl]oleamide (EC: 203-661-5)
9-Octadecenamide, N-3-(dimethylamino)propyl-, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Fatty acid amido propyl dimethylamines: Human health tier II assessment
Hazard Classes and Categories
Skin Corr. 1 (18.2%)
Skin corrosion - category 1
Toxicology
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Oleamidopropyl Dimethylamine
U.S. Production2023: 1,000,000 - <2,500,000 lb
Consumer UsesFuel agents
Industry UsesIntermediate
Use ClassificationCosmetics -> Antistatic
General Manufacturing Information
Petroleum Lubricating Oil and Grease Manufacturing
9-Octadecenamide, N-[3-(dimethylamino)propyl]-, (9Z)-: ACTIVE
Applications
UsesOleamidopropyl dimethylamine is a cationic emulsifier in cosmetics, such as body lotions, creams, shampoos, hair rinse preparations, etc.
Related reactions
1 records
Compound notes
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