Basic information
- CAS
53783-83-8- Standard SMILES
CN(C)CCOCC(=O)NC12CC3CC(CC(C3)C1)C2- InChIKey
UXQDWARBDDDTKG-UHFFFAOYSA-N- Molecular formula
- C16H28N2O2
- Average molar mass
- 280.41 g/mol
- Monoisotopic mass
- 280.21507814
Overview
Tromantadine is a secondary carboxamide.
Names & identifiers
- Preferred name
- Tromantadine
- IUPAC
- N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide
- English name
- tromantadine
- Molecular formula
- C16H28N2O2
- Molecular weight
- 280.41
Names & synonyms
Tromantadine53783-83-8TromantadinatromantadinTromantadinumH191JFG8WADTXSID00202062tromantidine2-(2-(Dimethylamino)ethoxy)-N-tricyclo(3.3.1.1(3,7))dec-1-ylacetamideN-(adamantan-1-yl)-2-[2-(dimethylamino)ethoxy]acetamideN-(Adamantan-1-yl)-2-(2-(dimethylamino)ethoxy)acetamideRefChem:192246
Show more names
Acetamide, 2-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-yl-
N-(1-adamantyl)-2-(2-dimethylaminoethoxy)acetamideD06BB02DTXCID00124553J05AC03258-770-0Tromantadine [INN:DCF]N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamideN-1-Adamantyl-2-(2-(dimethylamino)ethoxy)acetamide
Database identifiers
- CAS
53783-83-8- PubChem CID
- 64377
- DTXSID
DTXSID00202062- ChEMBL
CHEMBL3989506- ChEBI
CHEBI:135163- UNII
- H191JFG8WA
Properties
Computed structural properties
- XLogP
- 2.1
- Topological polar surface area
- 41.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 6
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 326
Physicochemical properties
- Boiling point
- 434.5 · 434.5±28.0 °C(Predicted)
- Density
- 1.09 · 1.09±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- form
- Oil
- pka
- 14.58 · 14.58±0.20(Predicted)
- color
- Colorless to light yellow
- FDA UNII
- 191 JFG8WA · H191JFG8WA
Chemistry & industry
Pharmacology
ATC Code
D - Dermatologicals
J - Antiinfectives for systemic use
QJ - Antiinfectives for systemic use
QD - Dermatologicals
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Applications
DescriptionTromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir.
UsesTromantadine hydrochloride is used as antiviral agent effective against herpes simplex infections.
Upstream & downstream products
Upstream raw materials
Suppliers19 total
北京华美互利生物化工010-56205725 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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