HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dactylyne
dactylyne · 2H-Pyran, 3-bromo-2-[(2E)-3-bromo-2-pentenyl]-5-chlorotetrahydro-6-(2Z)-2-penten-4-ynyl-, (2R,3R,5S,6S)- (9CI)
Identifiers & Physical Properties
| CAS No. | 55306-12-2 |
|---|---|
| Molecular formula | C15H19Br2ClO |
| Average molar mass | 410.57 g/mol |
| Monoisotopic mass | 407.94912 g/mol |
| SMILES | C#C/C=C/C[C@@H]1O[C@H](C/C=C(\Br)CC)[C@H](Br)C[C@@H]1Cl |
| InChIKey | NZHWXNQBZKBACG-XYQJUIJZSA-N |
| PubChem CID | 6441069 |
Chemical & Physical Properties
| XLogP | 5.3 |
|---|---|
| Topological polar surface area | 9.2 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 5 |
| Heavy atoms | 19 |
| Formal charge | 0 |
| Complexity | 383 |
| Boiling point | 439.1±45.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
Applications & Uses
Description
Dactylyne, an acetylenic dibromochloro ether, was isolated from the sea hare Aplysia dactylomela and characterized pharmacologically. It had no direct effect on the cardiovascular, respiratory, and central nervous systems of mice, rats, and guinea pigs. Dactylyne is new drug metabolism inhibitor of marine origin.
Uses
Dactylyne is an ethyl dibromochloroether isolated from the sea hare Dactylomela. Dactylyne has the ability to inhibit Pentobarbital (PTB) metabolism and potentiate the effects of other hypnotic drugs[1].