Basic information
- CAS
210344-97-1- Standard SMILES
COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(C)C)C(=O)CF- InChIKey
MVPQJUFFTWWKBT-LBDWYMBGSA-N- Molecular formula
- C31H39FN4O9
- Average molar mass
- 630.7 g/mol
- Monoisotopic mass
- 630.270107
Names & identifiers
- Preferred name
- Z-Yvad-fmk
- IUPAC
- methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxopentanoate
- English name
- MVPQJUFFTWWKBT-LBDWYMBGSA-N
- Molecular formula
- C31H39FN4O9
- Molecular weight
- 630.66
Names & synonyms
Z-YVAD-FMK210344-97-1Z-Tyr-Val-Ala-Asp(OMe) fluoromethyl ketoneCaspase-1 Inhibitor VImethyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxopentanoateZ-Tyr-Val-Ala-Asp(OMe)-FluoromethylketoneZ-YVAD(OMe)-FMKZ-Tyr-Val-Ala-Asp(OMe)-FMKZ-YVAD-FMK?GTPL5302orb1296602SCHEMBL28714059
Show more names
Z-YVAD-FMK, 10 mM in DMSOMVPQJUFFTWWKBT-LBDWYMBGSA-NZ-YVAD-FMK, Irreversible caspase-1 inhibitorCaspase 4,Inhibitor,Anti-inflammatory,ZYVADFMK,Caspase 1,Z YVAD FMK,Caspase,inhibit,anti-tumorL-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]- (9CI)
benzyloxycarbonyl-Tyr-Val-Ala-Asp(OMe)-fluoromethylketoneDTXSID10943333HY-P1009EX-A14804TP1466AKOS040764018DA-68894MS-30851
Properties
Computed structural properties
- XLogP
- 1.9
- Topological polar surface area
- 189 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 18
- Heavy atoms
- 45
- Formal charge
- 0
- Complexity
- 1,010
Physicochemical properties
- Boiling point
- 945.2 · 945.2±65.0 °C(Predicted)
- Density
- 1.261 · 1.261±0.06 g/cm3(Predicted)
- form
- Solid
- pka
- 9.81 · 9.81±0.15(Predicted)
- color
- White to off-white
- Sequence
- Z-Tyr-Val-Ala-Asp-FMK
Chemistry & industry
Applications
UsesZ-YVAD-FMK is acell-permeablecaspase-1 and -4 inhibitor withanti-inflammatory and anti-tumor activities[1].
Suppliers22 total
上海海皋科技有限公司021-57646680 18306277365 · [email protected]
Aladdin Scientific[email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
南京百鑫德诺生物科技有限公司025-58849295 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
风咏生物（AbMole）021-10000000 13000000000 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海正钇医药科技有限公司17740884366 · [email protected]
杭州肽佳生物科技有限公司0571-87213919 15967184799 · [email protected]
范德(北京)生物科技有限责任公司15911056312 · [email protected]
长沙福臻生物科技有限公司15111215862 18229892877 · [email protected]
江西研肽生物医药科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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