Basic information
- CAS
83482-58-0- Standard SMILES
COC1CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(C(C)CC2CCC(O)C(OC)C2)CC(=O)C(C)/C=C(\C)C(O)CC(=O)C(C)CC(C)/C=C/C=C/C=C/1C- InChIKey
SRIDGLJAFSFWOP-XOPIUEIMSA-N- Molecular formula
- C50H77NO12
- Average molar mass
- 884.1 g/mol
- Monoisotopic mass
- 883.54457689
Overview
produced by the action of Streptomyces hygroscopicus on rapamycin
Names & identifiers
- Preferred name
- Demethoxyrapamycin
- IUPAC
- (16E,24E,26E,28E)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
- English name
- 32-Desmethoxyrapamycin 1gm
- Molecular formula
- C50H77NO12
- Molecular weight
- 884.16
Names & synonyms
DemethoxyrapamycinDTXSID70860653AY-2466883482-58-0RefChem:919832DTXCID201511395DesmethoxyrapamycinAY 24668SRIDGLJAFSFWOP-XOPIUEIMSA-N(16E,24E,26E,28E)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone(3S,6R,7E,9S,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)propan-2-yl)-21-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaoneWAY-24688
Show more names
Antibiotic AY-2466832-Demethoxyrapamycin32-O-DesmethoxyrapamycinRapamycin, 32-demethoxy-32-Desmethoxyrapamycin 1gm32-DESMETHOXYRAPAMYCIN 10MG32-DESMETHOXYRAPAMYCIN 40MG
Properties
Computed structural properties
- XLogP
- 6
- Topological polar surface area
- 186 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 5
- Heavy atoms
- 63
- Formal charge
- 0
- Complexity
- 1,700
Physicochemical properties
- Boiling point
- 961.3 · 961.3±75.0 °C(Predicted)
- Density
- 1.17 · 1.17±0.1 g/cm3(Predicted)
- pka
- 10.4 · 10.40±0.70(Predicted)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory InformationRapamycin, 32-demethoxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Chemistry & industry
Applications
UsesDemethoxy Rapamycin is an antifungal agent that is highly effective in inhibiting the growth of yeast and mold strains. An immunosuppressant.
Suppliers13 total
济南百隆化学有限公司[email protected] · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
湖北扬信医药科技有限公司15347293736 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
Standardpharm Co. Ltd.86-714-3992388 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
深圳瑞恺德生物科技有限公司0755-61348847 17820674378 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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