Basic information
- CAS
111278-01-4- Standard SMILES
CC(/C=C/C1CC=CC(=O)O1)=C\C(C)C/C=C/C(C)=C/C(C)C(=O)C(C)C(O)C(C)C/C(C)=C/C(=O)O- InChIKey
SGYKTDIJCLHSET-UHFFFAOYSA-N- Molecular formula
- C31H44O6
- Average molar mass
- 512.7 g/mol
- Monoisotopic mass
- 512.31378912
Overview
Anguinomycin A has been reported in Streptomyces with data available.
Names & identifiers
- Preferred name
- Anguinomycin A
- IUPAC
- (2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-19-(6-oxo-2,3-dihydropyran-2-yl)nonadeca-2,10,12,16,18-pentaenoic acid
- English name
- anguinomycin A
- Molecular formula
- C31H44O6
- Molecular weight
- 512.68
Names & synonyms
Anguinomycin A111278-01-4(2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-19-(6-oxo-2,3-dihydropyran-2-yl)nonadeca-2,10,12,16,18-pentaenoic acid2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-RefChem:112730AKOS025294088AKOS040755891HY-126740CS-0107058T37542KR-2827B5-DeMethylleptoMycin A, KR 2827A
Show more names
19-[(3,6-Dihydro-6-oxo-2H-pyran)-2-yl]-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid
Database identifiers
- CAS
111278-01-4- PubChem CID
- 6444136
- Nikkaji
- J410.829I
Properties
Computed structural properties
- XLogP
- 7.1
- Topological polar surface area
- 101 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 14
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 978
Physicochemical properties
- Boiling point
- 714.9 · 714.9±60.0 °C(Predicted)
- Density
- 1.095 · 1.095±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- DMSO: Unstable; Ethanol: Soluble; Methanol: Soluble
- form
- Pale yellow film.
- pka
- 5.11 · 5.11±0.33(Predicted)
Chemistry & industry
Applications
UsesAnguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in vivo against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of leptomycin B, an inhibitor of nuclear export of proteins.
Suppliers19 total
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
上海一研生物科技有限公司021-69985186 13611928337 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
西安莱茵生物科技有限公司86-(0)29-85992781 17792393971 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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