Basic information
- CAS
97635-31-9- Standard SMILES
O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([O-])[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)CO.[Ca+2]- InChIKey
YPCRNBPOUVJVMU-LCGAVOCYSA-L- Molecular formula
- C18H32CaO19
- Average molar mass
- 592.5 g/mol
- Monoisotopic mass
- 592.1163696
Overview
Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Names & identifiers
- Preferred name
- (4-O-beta-D-Galactopyranosyl-D-gluconato-O1)(D-gluconato-O1)calcium
- IUPAC
- calcium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate
Names & synonyms
97635-31-9UNII-93H20IU3DN(4-O-beta-D-Galactopyranosyl-D-gluconato-O1)(D-gluconato-O1)calciumEINECS 307-393-0EBC-27362DB13142calcium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoateCalcium, (4-O-beta-D-galactopyranosyl-D-gluconato-O1)(D-gluconato-O1)-
Database identifiers
- CAS
97635-31-9- PubChem CID
- 64776
- EC Number
- 307-393-0
Properties
Computed structural properties
- Topological polar surface area
- 362 Ų
- Hydrogen bond donors
- 13
- Hydrogen bond acceptors
- 19
- Rotatable bonds
- 15
- Heavy atoms
- 38
- Formal charge
- 0
- Complexity
- 686
Chemistry & industry
Pharmacology
Protein Binding~40%, primarily to albumin
Mechanism of Action
Essential for nervous, muscular, and skeletal systems. Maintain cell membrane and capillary permeability. Act as an activator in the transmission of nerve impulses and contraction of cardiac, skeletal, and smooth muscle. Essential for bone formation and blood coagulation.
Absorption, Distribution and Excretion
Minimal unless chronic, high doses; absorption predominantly in the duodenum and dependent on calcitriol and vitamin D; mean absorption of calcium intake varies with age (infants 60%, prepubertal children 28%, pubertal children 34%, adults 25%); during pregnancy, calcium absorption doubles; calcium is absorbed in soluble, ionized form; solubility of calcium is increased in an acid environment (IOM 2011); decreased absorption occurs in patients with achlorhydria, renal osteodystrophy, steatorrhea, or uremia
Primarily feces (75%; as unabsorbed calcium); urine (22%)
Primarily in bones, teeth
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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