Basic information
- CAS
57197-43-0- Standard SMILES
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC.Cc1nc(NS(=O)(=O)c2ccc(N)cc2)oc1C- InChIKey
QSCDJPXGCZNSNJ-UHFFFAOYSA-N- Molecular formula
- C25H31N7O6S
- Average molar mass
- 557.6 g/mol
- Monoisotopic mass
- 557.20565291
Names & identifiers
- Preferred name
- Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine
- IUPAC
- 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- English name
- co-trifamole
- Molecular formula
- C14H18N4O3.C11H13N3O3S
- Molecular weight
- 557.629
Names & synonyms
57197-43-0DTXSID10205827Benzenesulfonamide, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-, mixt. with 5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamineRefChem:1078651DTXCID40128318SupristolCo-trifamolecotrifamolecotrifamolSulfamoxole and trimethoprimTrimethoprim and sulfamoxoleSulfamoxazole + trimethoprim
Show more names
Mixture with trimethoprim
CN 3123CN-3123Sulfamoxole - trimethoprimSulfamoxole, trimethoprim drug combination4-Amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide--5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine (1/1)
Database identifiers
- CAS
57197-43-0- PubChem CID
- 64937
- DTXSID
DTXSID10205827
Properties
Computed structural properties
- Topological polar surface area
- 212 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 13
- Rotatable bonds
- 8
- Heavy atoms
- 39
- Formal charge
- 0
- Complexity
- 680
Physicochemical properties
- Toxicity
- 50 in · LD50 in mice, rats (g/kg): >12.0, 14.0 orally; 1.87, 2.00 i.p. (Lagler)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 in mice, rats (g/kg): >12.0, 14.0 orally; 1.87, 2.00 i.p. (Lagler)
Chemistry & industry
Pharmacology
ATC CodeJ - Antiinfectives for systemic use
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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