Meglumine Antimoniate
Basic information
- CAS
133-51-7- Standard SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[O]=[Sb](=[O])[OH]- InChIKey
XOGYVDXPYVPAAQ-SESJOKTNSA-M- Molecular formula
- C7H18NO8Sb
- Average molar mass
- 365.98 g/mol
- Monoisotopic mass
- 365.00705
Overview
ANTIMONY salt of meglumine that is used in the treatment of LEISHMANIASIS.
Names & identifiers
- Preferred name
- Meglumine Antimoniate
- IUPAC
- hydroxy(dioxo)-λ5-stibane;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
- English name
- Methylglucamine antimonate
- Molecular formula
- C7H18NO8Sb
- Molecular weight
- 365.98
Names & synonyms
Glucantimemeglumine antimoniateMeglumine antimonate133-51-7N-Methylglucamine antimonateGlucantim1-Deoxy-1-(methylamino)glucitol antimonate(V)DTXSID404393575G4TW236W(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; oxostibinic acidN Methylglucamine AntimonateRefChem:156280
Show more names
meglumineantimonateMEGLUMINANTIMONIATEhydroxy(diketo)stiboranemethylglucamineantimonateN-MethylgluamineAntimoniateJIRQMKPLRAUDQF-OVHUINQISA-KN-METHYL GLUCAMINE ANTIMONATE
DTXCID2023935205-108-3Methylglucamine antimonateProtostibn-methyl glucamine antimoniateN-Methylgluamine AntimoniateN-methylglucamine antimoniate2168-RP
Database identifiers
- CAS
133-51-7- PubChem CID
- 64953
- DTXSID
DTXSID4043935- ChEMBL
Properties
Computed structural properties
- Topological polar surface area
- 168 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 6
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 180
Experimental & physicochemical properties
Human DrugsAntileishmaniasis medicines
Physicochemical properties
- storage temp.
- Refrigerator, Under inert atmosphere
- solubility
- Acidic DMSO (Slightly, Sonicated), Aqueous Base (Very Slightly, Heated)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1/C7H17NO5.3O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;;;;/q;;;;-1/p+1/t4-,5+,6+,7+;;;;/s3
- InChIKey
- JLGCKKAHTCRITP-GZLWXHMYNA-O
- SMILES
- [C@@H](O)([C@@H](O)CNC)[C@H](O)[C@H](O)CO.[Sb-](=O)(=O)=O.[H+] |&1:0,2,7,9,r|
- CAS DataBase Reference
- 133 · 133-51-7(CAS DataBase Reference)
- FDA UNII
- 75 G4TW236W · 75G4TW236W
- ATC code
- 1 CB01 · P01CB01
- EPA Substance Registry System
- Glucantime (133-51-7)
- Symbol(GHS)
- 7 · GHS07,GHS09
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.
Warning
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P271, P273, P301+P317, P304+P340, P317, P330, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (50%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07,GHS09
- Hazard statements
- H332-H411-H302
- Precautionary statements
- P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
ATC Code
P - Antiparasitic products, insecticides and repellents
QP - Antiparasitic products, insecticides and repellents
P01CB01
MeSH Pharmacological ClassificationSubstances that are destructive to protozoans.
Applications
UsesIn the synthesis of surface active agents, pharmaceuticals, dyes.
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Related reactions
0 records
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Compound notes
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