Basic information
- CAS
85236-92-6- Standard SMILES
[N-]=[N+]=N[C@H]1C[C@H](n2cc(I)c(=O)[nH]c2=O)O[C@@H]1CO- InChIKey
RKFULXUNGOGTPS-RRKCRQDMSA-N- Molecular formula
- C9H10IN5O4
- Average molar mass
- 379.11 g/mol
- Monoisotopic mass
- 378.97775
Overview
a potent, selective inhibitor of HIV replication
Names & identifiers
- Preferred name
- 3'-Azido-2',3'-dideoxy-5-iodouridine
- IUPAC
- 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
- English name
- 3'-azido-2',3'-dideoxy-5-iodouridine
- Molecular formula
- C9H10IN5O4
- Molecular weight
- 379.11127
Names & synonyms
Azidurd3'-Azido-2',3'-dideoxy-5-iodouridine85236-92-6DTXSID10234435RefChem:90310DTXCID10156926Uridine, 3'-azido-2',3'-dideoxy-5-iodo-AZddIU5-I-AZU3'-N3-5-I-ddUCHEMBL1791030SCHEMBL27897239
Show more names
PD2016861-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione
Database identifiers
- CAS
85236-92-6- PubChem CID
- 64979
- DTXSID
DTXSID10234435- ChEMBL
CHEMBL1791030- Nikkaji
- J400.856A
Properties
Computed structural properties
- XLogP
- 0.3
- Topological polar surface area
- 93.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 489
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
Suppliers1 total
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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