Basic information
- CAS
1431-39-6- Standard SMILES
CN(C)c1cccc2c(S(N)(=O)=O)cccc12- InChIKey
TYNBFJJKZPTRKS-UHFFFAOYSA-N- Molecular formula
- C12H14N2O2S
- Average molar mass
- 250.32 g/mol
- Monoisotopic mass
- 250.07759887
Names & identifiers
- Preferred name
- Dansylamide
- IUPAC
- 5-(dimethylamino)naphthalene-1-sulfonamide
- English name
- DANSYLAMIDE
- Molecular formula
- C12H14N2O2S
- Molecular weight
- 250.32
Names & synonyms
Dansylamide1431-39-65-(dimethylamino)naphthalene-1-sulfonamide5-Dimethylaminonaphthalene-1-sulfonamideDNSAdansylsulfonamide1-Naphthalenesulfonamide, 5-(dimethylamino)-Dansyl-1-sulfonamideZUZ5S5875EDTXSID701623061-Dimethylaminonaphthalene-5-sulfonamideRefChem:130891
Show more names
Dan amideDansylamide,99%DansylaMide, 99% 1GRDansyl amide, DNSADansylamide, 10 mM in DMSOinhibit,Inhibitor,DansylamideDansylamide[forFluorometry]>
DTXCID8084797215-854-15-(DIMETHYLAMINO)-1-NAPHTHALENESULFONAMIDE5-DIMETHYLAMINO-1-NAPHTHALENESULFONAMIDEMFCD000040005-(Dimethylamino)naphthalene-1-sulphonamideDansyl amideDANSYLAMIDE [FOR FLUOROMETRY]
Database identifiers
- CAS
1431-39-6- PubChem CID
- 65077
- DTXSID
DTXSID70162306- ChEMBL
CHEMBL119489- UNII
- ZUZ5S5875E
- EC Number
- 215-854-1
- Nikkaji
- J208.366C
Properties
Computed structural properties
- XLogP
- 2
- Topological polar surface area
- 71.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 361
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
LogP1.83
Physicochemical properties
- Melting point
- 218 · 218-221 °C(lit.)
- Boiling point
- 435.4 · 435.4±37.0 °C(Predicted)
- Density
- 1.2391 · 1.2391 (rough estimate)
- refractive index
- 1.595 · 1.5950 (estimate)
- storage temp.
- 20 °C · −20°C
- solubility
- soluble in Dimethylformamide
- form
- Fine Crystalline Powder
- pka
- 10.29 · 10.29±0.30(Predicted)
- color
- White to light yellow
- BRN
- 2217203 · 2217203
- InChI
- InChI=1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)
- InChIKey
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory InformationChemical: 1-Naphthalenesulfonamide, 5-(dimethylamino)-
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- hs_code
- 29350090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 22-24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H319
- Precautionary statements
- P305+P351+P338
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Applications
Uses5-(Dimethylamino)-1-naphthalenesulfonamide (DNSA) was used as starting reagent in the synthesis of 2,6-disubstituted pyridines, 6-substituted 2,2′-bipyridines and 6,6′-disubstituted 2,2′-bipyridines. It was also used as fluorescent probe in the determination of concentration of human carbonic anhydrase II-DNSA in solutions.
Suppliers76 total
山东玖玥生物科技有限公司15553333686 · [email protected]
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
陕西格列弗生物科技研究有限责任公司18409274651; 13892423764 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
苏州奥佰医药科技有限公司
Related reactions
5 records
Compound notes
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