Basic information
- CAS
4537-78-4- Standard SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCCCC- InChIKey
FVJZSBGHRPJMMA-UHFFFAOYSA-N- Molecular formula
- C42H83O10P
- Average molar mass
- 779.1 g/mol
- Monoisotopic mass
- 778.57238584
Overview
Distearoyl phosphatidylglycerol is a phosphatidylglycerol in which the phosphatidyl acyl groups are both stearoyl.
Names & identifiers
- Preferred name
- Distearoylphosphatidylglycerol
- IUPAC
- [3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
- English name
- 1,2-Distearoyl-sn-glycero-3-phosphoglycerol,sodium salt
- Molecular formula
- C42H83O10P
- Molecular weight
- 779.08
Names & synonyms
Distearoyl phosphatidylglycerol4537-78-4DSPGDistearoyl ppgDistearoylphosphatidylglycerol4271ZA8WXOCHEBI:61056DISTEAROYLPHOSPHATIDYLGLYCEROL, DL-Octadecanoic acid, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl esterRefChem:9205083-(((2,3-dihydroxypropoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl distearate1,2-Distearoyl-sn-glycero-3-phosphorylglycerol
Show more names
Diastearoyl phosphatidylglycerol1,2-distearoylphosphatidylglycerol1,2-Distearoyl-sn-glycero-3-phosphorylglycerol(DSPG)1,2-distearoyl-sn-glycero-3-phosphatidyl-rac-glycerol1,2-Distearoyl-sn-glycero-3-phosphorylglycerol (Na+?salt)1,2-Distearoyl-sn-glycero-3-phosphorylglycerol sodium salt (DSPG), Phosphorylglycerolstearic acid [1-[[glyceryloxy(hydroxy)phosphoryl]oxymethyl]-2-stearoyloxy-ethyl] ester[1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-octadecanoyloxypropan-2-yl] octadecanoate
Properties
Computed structural properties
- XLogP
- 14.3
- Topological polar surface area
- 149 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 44
- Heavy atoms
- 53
- Formal charge
- 0
- Complexity
- 858
Physicochemical properties
- Melting point
- 66.5 · 66.5-67.0 °C
- Boiling point
- 796.4 · 796.4±70.0 °C(Predicted)
- Density
- 1.026 · 1.026±0.06 g/cm3(Predicted)
- pka
- 1.39 · 1.39±0.50(Predicted)
- FDA UNII
- 4271 ZA8WXO · 4271ZA8WXO
Chemistry & industry
Applications
Uses1,2-Distearoyl-sn-glycero-3-phosphorylglycerol is used as a component of a loposomal delivery system that coordinates the release of irinotecan and floxuridine in vivo. It is also used to encapsulate anthracyclines and deliver them to tumors.
Upstream & downstream products
Upstream raw materials
Suppliers18 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
广东方信生物科技有限公司0751-2838688 13376594225 · [email protected]
广东元丰化学试剂有限公司0751-2829979 13376591640 · [email protected]
广东顺奥化学试剂有限公司19928586137 · [email protected]
上海丽康新材料有限公司+86-16631818819 +86-17736933208 · [email protected]
上海安奕康生物科技有限公司021-021-20956531 15121039011 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
Related reactions
1 records
Compound notes
Loading…