CAS 50-98-6 Ephedrine Hydrochloride (HCID 65326)

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Basic information

CAS: 50-98-6
Standard SMILES: CN[C@@H](C)[C@H](O)c1ccccc1.Cl
InChIKey: BALXUFOVQVENIU-GNAZCLTHSA-N
Molecular formula: C10H16ClNO
Average molar mass: 201.69 g/mol
Monoisotopic mass: 201.09204181

Overview

Ephedrine hydrochloride is an alkylbenzene.

Names & identifiers

Preferred name: Ephedrine Hydrochloride
IUPAC: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;hydrochloride

Names & synonyms

Ephedrine hydrochloride50-98-6(-)-Ephedrine hydrochlorideL-Ephedrine hydrochlorideEPHEDRINE HCLDTXSID1045825REZIPRESNLJ6390P1ZEphedrini hydrochloridumNSC-759611DTXCID9025825Benzenemethanol, alpha-(1-(methylamino)ethyl)-, hydrochloride, (R-(R*,S*))-

Show more names

Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, hydrochloride, (alphaR)-BronchipaxTaumasthmanAsmapaxExpurhinTabasanSecronEphed hcl

Database identifiers

CAS: 50-98-6
PubChem CID: 65326
DTXSID: DTXSID1045825
ChEMBL: CHEMBL2146102
ChEBI: CHEBI:31541
UNII: NLJ6390P1Z
EC Number: 200-074-6

Properties

Computed structural properties

Topological polar surface area: 32.3 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 2
Rotatable bonds: 3
Heavy atoms: 13
Formal charge: 0
Complexity: 121

Experimental & physicochemical properties

Human Drugs · 2 items

FDA approved drugs -> Active ingredient

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 114 reports by companies from 7 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory Information · 2 items

Status: Active Update: 08-11-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/10058

Ephedrine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Benzenemethanol, .alpha.-[1-(methylamino)ethyl]-, hydrochloride, [R-(R*,S*)]-: Environment tier I assessment

Hazard Classes and CategoriesAcute Tox. 4 (100%)

Chemistry & industry

Pharmacology

FDA Pharmacological Classification · 2 items

EPHEDRINE HYDROCHLORIDE

Increased Norepinephrine Activity [PE]; Norepinephrine Releasing Agent [EPC]; Adrenergic beta-Agonists [MoA]; Adrenergic alpha-Agonists [MoA]; alpha-Adrenergic Agonist [EPC]; beta-Adrenergic Agonist [EPC]

MeSH Pharmacological Classification · 4 items

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Drugs used to cause constriction of the blood vessels.

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.