Basic information
- CAS
29706-85-2- Standard SMILES
Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O- InChIKey
OIFWQOKDSPDILA-XLPZGREQSA-N- Molecular formula
- C10H14N5O7P
- Average molar mass
- 347.22 g/mol
- Monoisotopic mass
- 347.0630848
Names & identifiers
- Preferred name
- Zidovudine Monophosphate
- IUPAC
- [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
- English name
- 3'-AZIDO-2',3'-DIDEOXY-THYMIDINE-5'-MONOPHOSPHATE, SODIUM SALT
- Molecular formula
- C10H14N5O7P
- Molecular weight
- 347.22
Names & synonyms
Zidovudine monophosphateAZT-MPazidothymidine monophosphate97YMU05VPJAZT 5'-MONOPHOSPHATE{[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid(((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl)methoxy)phosphonic acidRefChem:90485829706-85-2Zidovudine 5'-monophosphateZdv 5'-monophosphate5'-Thymidylic acid, 3'-azido-3'-deoxy-
Show more names
Zidovudine M1AZTMP SODIUM SALTZidovudinemonophosphateAZT MONOPHOSPHATE, SODIUM SALT3'-AzidothyMidine Monophosphate3’-azido-3’-deoxythymidine5’phosphate5′-Thymidylic acid, 3′-azido-3′-deoxy-AZT monophosphate sodium-potassium salt3'-azido-2',3'-dideoxythymidine monophosphate
3'-Azido-3'-deoxythymidine 5'-Monophosphate Sodium Salt3'-Azido-2',3'-deoxythymidine 5'-monophosphate[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate128506-29-63'-azido-3'-deoxythymidine 5'-(dihydrogen phosphate)3'-azido-3'-deoxythymidine-5'-monophosphateAzddTMP3'-azido-3'-deoxythymidine monophosphate
Properties
Computed structural properties
- XLogP
- -1
- Topological polar surface area
- 140 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 5
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 640
Experimental & physicochemical properties
Drugs
Pharmaceuticals -> Listed in ZINC15
Pharmaceuticals -> Metabolite of Zidovudine
Physicochemical properties
- Melting point
- 154 · 154-160°C (dec.)
- storage temp.
- 20 °C · −20°C
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
- form
- Solid
- pka
- 1.856 · 1.856±0.10(predicted)
- color
- White to Pale Beige
- FDA UNII
- 97 YMU05VPJ · 97YMU05VPJ
- Hazard Codes
- Xn
- Risk Statements
- 20 · 20/21/22
- Safety Statements
- 36 · 36
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- risk_code
- 20/21/22
- hazard_code
- Xn
- safety_code
- 36
Chemistry & industry
Applications
UsesA metabolite of the potent and selective inhibitor of HIV-1 replication, AZT
Upstream & downstream products
Downstream products
Suppliers15 total
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
吉林中科研伸科技有限公司18143011203 · [email protected]
Clearsynth Labs Limited+91-22-26355700 · [email protected]
凯试（上海）科技有限公司
Related reactions
1 records
Compound notes
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