Basic information
- CAS
16188-61-7- Standard SMILES
CN(C)CCn1nc(Cc2ccccc2)c2ccccc2c1=O- InChIKey
LCAAMXMULMCKLJ-UHFFFAOYSA-N- Molecular formula
- C19H21N3O
- Average molar mass
- 307.4 g/mol
- Monoisotopic mass
- 307.1684623
Overview
Talastine is a member of phthalazines.
Names & identifiers
- Preferred name
- Talastine
- IUPAC
- 4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1-one
- English name
- Talastine
- Molecular formula
- C19H21N3O
- Molecular weight
- 307.39
Names & synonyms
Talastine16188-61-7TalastinaTalastinum49AB2PA48BDTXSID201672654-benzyl-2-[2-(dimethylamino)ethyl]-1,2-dihydrophthalazin-1-one4-benzyl-2-(2-dimethylaminoethyl)phthalazin-1-(2H)-one4-benzyl-2-(2-(dimethylamino)ethyl)-1,2-dihydrophthalazin-1-oneRefChem:187293DTXCID7089756R06AB07
Show more names
1(2H)-Phthalazinone, 2-[2-(dimethylamino)ethyl]-4-(phenylmethyl)-
Talastine [INN]4-Benzyl-2-(2-(dimethylamino)ethyl)phthalazin-1(2H)-one4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1-oneTalastine (INN)4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1(2H)-oneTalastinum [INN-Latin]Talastina [INN-Spanish]UNII-49AB2PA48B
Database identifiers
- CAS
16188-61-7- PubChem CID
- 65624
- DTXSID
DTXSID20167265- ChEMBL
CHEMBL1742439- ChEBI
CHEBI:135308- UNII
- 49AB2PA48B
- Nikkaji
- J9.030A
Properties
Computed structural properties
- XLogP
- 2.8
- Topological polar surface area
- 35.9 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 440
Physicochemical properties
- Melting point
- 107 · 107-108 °C(Solv: water (7732-18-5); acetone (67-64-1))
- Boiling point
- 0.3 · bp0.3 215-222°
- Density
- 1.11 · 1.11±0.1 g/cm3(Predicted)
- pka
- 8.84 · 8.84±0.28(Predicted)
- FDA UNII
- 49 AB2PA48B · 49AB2PA48B
- ATC code
- 6 AB07 · R06AB07
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Pharmacology
ATC Code
R - Respiratory system
QR - Respiratory system
Metabolite PathwaysTalastine H1-Antihistamine Action
Applications
UsesTalastine is a potent H1-antihistamine. Talastine can induce allergic exanthema[1][2].
Suppliers5 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Alchem Pharmtech,Inc.8485655694 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Additional notes
DefinitionChEBI: Talastine is a member of phthalazines.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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