Basic information
- CAS
17127-48-9- Standard SMILES
COc1cc2c3c(c1O)C1(C=CC(=O)C=C1)CC3N(C)CC2- InChIKey
PNJUPRNTSWJWAX-UHFFFAOYSA-N- Molecular formula
- C18H19NO3
- Average molar mass
- 297.3 g/mol
- Monoisotopic mass
- 297.13649347
Overview
Glaziovine has been reported in Annona cherimola and Litsea cubeba with data available.
Names & identifiers
- Preferred name
- Glaziovine
- IUPAC
- 11-hydroxy-10-methoxy-5-methylspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene]-1'-one
- English name
- Glaziovine
- Molecular formula
- C18H19NO3
- Molecular weight
- 297.35
Names & synonyms
GlaziovineGlaziovinumNSC-146052KE7J8A65P611-hydroxy-10-methoxy-5-methylspiro[5-azatricyclo[6.3.1.04,12]dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene]-1'-oneDTXSID00103182211-hydroxy-10-methoxy-5-methylspiro(5-azatricyclo(6.3.1.04,12)dodeca-1(12),8,10-triene-2,4'-cyclohexa-2,5-diene)-1'-oneRefChem:143318DTXCID701516821229-883-217127-48-9Glaziovine [INN]
Show more names
Ai3-34588Nsc 146052(±)-GlaziovineUnii-ke7J8A65p6Glaziovinum [inn-latin]Glaziovina [inn-spanish]
Glaziovina(+/-)-Glaziovine6'-Hydroxy-5'-methoxy-1'-methyl-2',3',8',8a'-tetrahydro-1'H-spiro[cyclohexa[2,5]diene-1,7'-cyclopenta[ij]isoquinolin]-4-oneNSC141545SuavedolGlaziovine, L-N-MethylcrotsparineCrotsparine, 6-methyl-
Database identifiers
- CAS
17127-48-9、6808-72-6
Properties
Computed structural properties
- XLogP
- 2.2
- Topological polar surface area
- 49.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 524
Physicochemical properties
- Melting point
- 227 · 227-228 °C
- Boiling point
- 470.8 · 470.8±45.0 °C(Predicted)
- Density
- 1.33 · 1.33±0.1 g/cm3(Predicted)
- pka
- 9.76 · 9.76±0.20(Predicted)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 7 J8A65P6 · KE7J8A65P6
Chemistry & industry
Applications
Uses(±)-Glaziovine, a proaporphine alkaloid, has anxiolytic activity. (±)-Glaziovine can be used for neuropharmacological research[1].
Upstream & downstream products
Upstream raw materials
Suppliers4 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
Alchem Pharmtech,Inc.8485655694 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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