Basic information
- CAS
103342-82-1- Standard SMILES
CN1C(=O)[C@@H](Cc2c[nH]c3ccccc23)N=C(c2ccccc2F)c2ccccc21- InChIKey
CGBANSGENFERAT-JOCHJYFZSA-N- Molecular formula
- C25H20FN3O
- Average molar mass
- 397.4 g/mol
- Monoisotopic mass
- 397.15904043
Overview
R-L3 is a benzodiazepine.
Names & identifiers
- Preferred name
- (3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one
- IUPAC
- (3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-one
- English name
- 5-(2-Fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-2H-1,4-benzodiazepin-2-one
- Molecular formula
- C25H20FN3O
- Molecular weight
- 397.45
Names & synonyms
103342-82-1R-L3L-364,373L-364373(3R)-5-(2-fluorophenyl)-3-(1H-indol-3-ylmethyl)-1-methyl-3H-1,4-benzodiazepin-2-oneCCK antagonist synthetic 11C13824AC1LCVITR-L364,373SureCN7515330L3643735-(2-FLUOROPHENYL)-1,3-DIHYDRO-3-(1H-INDOL-3-YLMETHYL)-1-METHYL-2H-1,4-BENZODIAZEPIN-2-ONE
Show more names
373L364,373,L 364,373Lecithin Impurity 13(D-Inositol)Devazepide Impurity 1 (L-364373)2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-3-(1H-indol-3-ylmethyl)-1-methyl-, (3R)-
GTPL2595orb1704439SCHEMBL7515330CHEMBL1907717SCHEMBL29392864BDBM82388CHEBI:34942DTXSID90349652
Database identifiers
- CAS
103342-82-1- PubChem CID
- 656755
Properties
Computed structural properties
- XLogP
- 4.8
- Topological polar surface area
- 48.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 667
Physicochemical properties
- Melting point
- 80 · 80-85 °C
- Boiling point
- 640.538 · 640.538±55.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.275 · 1.275±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- 4 °C · Store at +4°C
- solubility
- 100 mM · Soluble to 100 mM in DMSO
- form
- Powder
- pka
- 17.064 · 17.064±0.30(predicted)
- color
- White to off-white
Chemistry & industry
Applications
UsesL-364,373 is a KCNQ1/mink channels activator.
Suppliers7 total
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
EMMX Biotechnology LLC888-539-0666 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
Additional notes
DefinitionChEBI: R-L3 is a benzodiazepine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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