Basic information
- CAS
53-60-1- Standard SMILES
CN(C)CCCN1c2ccccc2Sc2ccccc21.[Cl-].[H+]- InChIKey
JIVSXRLRGOICGA-UHFFFAOYSA-N- Molecular formula
- C17H21ClN2S
- Average molar mass
- 320.9 g/mol
- Monoisotopic mass
- 320.1113975
Overview
Promazine hydrochloride is a hydrochloride. It contains a promazine.
Names & identifiers
- Preferred name
- 10H-Phenothiazine-10-propanamine, N,N-dimethyl-,monohydrochloride
- IUPAC
- N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine;hydron;chloride
- English name
- Promazine hydrochloride
- Molecular formula
- C17H21ClN2S
- Molecular weight
- 320.88
Names & synonyms
10H-Phenothiazine-10-propanamine, N,N-dimethyl-,monohydrochlorideSCHEMBL123419AKOS026749940rp4560LiranolPrazineRP 4560SparineTalofenVerofenMegaphenPromwill
Show more names
Starazin
Database identifiers
- CAS
53-60-1- PubChem CID
- 657285
- ChEBI
CHEBI:8460
Properties
Computed structural properties
- Topological polar surface area
- 31.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 285
Physicochemical properties
- Melting point
- 174 · 174-176C
- Density
- 1.1435 · 1.1435 (rough estimate)
- refractive index
- 1.6 · 1.6000 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White
- BRN
- 3753230 · 3753230
- Major Application
- clinical testing
- InChI
- 1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H
- InChIKey
- JIVSXRLRGOICGA-UHFFFAOYSA-N
- SMILES
- Cl[H].CN(C)CCCN1c2ccccc2Sc3ccccc13
- CAS DataBase Reference
- 53 · 53-60-1(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 16 EOR79U4 · U16EOR79U4
- NIST Chemistry Reference
- -10 H-phenothiazine-1-propanamine · N,N-dimethyl-10H-phenothiazine-1-propanamine hydrochloride(53-60-1)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Faceshields, Gloves
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- SO8575000
- hs_code
- 2934302300
- risk_code
- 22-43
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H317
- Hazard Classifications
- Acute Tox. 4 OralSkin Sens. 1
- Precautionary statements
- P280-P301+P312+P330
Chemistry & industry
Applications
UsesPromazine hydrochloride has been used in conductivity and surface tension measurements and for testing inhibition of feline coronavirus (FCoV) in Felis catus whole fetus-4 (fcwf-4) cells.
UsesAntipsychotic. Tranquilizer.
General DescriptionPromazine hydrochloride (PMZ) belongs to the phenothiazine drug family. Promazine is a D2 dopamine receptor antagonist and has antipsychotic and anticholinergic functionality. It is used for pain management and is also used for treating hypersensitivity reactions.
Suppliers80 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
Syntechem Co.,Ltd[email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…