Terofenamate
Basic information
- CAS
29098-15-5- Standard SMILES
CCOCOC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl- InChIKey
FRQSLQPWXFAJFO-UHFFFAOYSA-N- Molecular formula
- C17H17Cl2NO3
- Average molar mass
- 354.2 g/mol
- Monoisotopic mass
- 353.0585488
Overview
Terofenamate is a small molecule drug. The usage of the INN stem '-fenamate' in the name indicates that Terofenamate is a "fenamic acid" derivative. Terofenamate has a monoisotopic molecular weight of 353.06 Da.
Names & identifiers
- Preferred name
- Terofenamate
- IUPAC
- ethoxymethyl 2-(2,6-dichloro-3-methylanilino)benzoate
- English name
- terofenamate
- Molecular formula
- C17H17Cl2NO3
- Molecular weight
- 0
Names & synonyms
TerofenamateEtoclofene29098-15-5TerofenamatoTerofenamatumA53154FC4NDTXSID20183344M-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl esterRefChem:188014DTXCID30105835249-434-4Terofenamate [INN]
Show more names
ethoxymethyl N-(2,6-dichloro-m-tolyl)-anthranilate2-[(2,6-Dichloro-m-tolyl)amino]benzoic acid ethoxymethyl ester2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid ethoxymethyl ester2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid ethoxymethyl ester
ethoxymethyl 2-(2,6-dichloro-3-methylanilino)benzoateEtofenEtofen; N-(2,6-Dichloro-m-tolyl)anthranilic acid ethoxymethyl esterTerofenamatum [INN-Latin]Terofenamato [INN-Spanish]EINECS 249-434-4BRN 2894433UNII-A53154FC4N
Database identifiers
- CAS
29098-15-5- PubChem CID
- 65763
- DTXSID
DTXSID20183344
Properties
Computed structural properties
- XLogP
- 5.8
- Topological polar surface area
- 47.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 7
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 383
Physicochemical properties
- Melting point
- 73 · 73-74°
- Density
- 1.3318 · 1.3318 (rough estimate)
- refractive index
- 1.614 · 1.6140 (estimate)
- FDA UNII
- 53154 FC4N · A53154FC4N
- Toxicity
- 50 in · LD50 in mice, rats (mg/kg): 918, 307 orally; 300, 274 i.p. (Chieli)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 in mice, rats (mg/kg): 918, 307 orally; 300, 274 i.p. (Chieli)
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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