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Glipalamide

HCID 65802
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Basic informationOverviewNames & identifiersPropertiesChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
37598-94-0
Standard SMILES
Cc1ccc(S(=O)(=O)NC(=O)N2N=CCC2C)cc1
InChIKey
OUUYOZGHNAGYNC-UHFFFAOYSA-N
Molecular formula
C12H15N3O3S
Average molar mass
281.33 g/mol
Monoisotopic mass
281.08341252

Overview

Glipalamide is a second-generation sulfonamide derivative with antihyperglycemic activity. Like other sulfonylureas, glipalamide exerts extra-pancreatic activity, such as increased binding of insulin to insulin receptors on adipocytes.

Names & identifiers

Preferred name
Glipalamide
IUPAC
3-methyl-N-(4-methylphenyl)sulfonyl-3,4-dihydropyrazole-2-carboxamide
English name
Glipalamide
Molecular formula
C12H15N3O3S
Molecular weight
281.33

Names & synonyms

Glipalamide37598-94-0GlipalamidaGlipalamidumGlipolamideSPC-703W7J490CUHM3-methyl-N-(4-methylphenyl)sulfonyl-3,4-dihydropyrazole-2-carboxamideSPC 7034,5-Dihydro-5-methyl-N-((4-methylphenyl)sulfonyl)-1H-pyrazole-1-carboxamideglipolamidRefChem:143381
Show more names
N-Tosyl-5-methyl-2-pyrazoline-1-carboxamide1H-Pyrazole-1-carboxamide, 4,5-dihydro-5-methyl-N-[(4-methylphenyl)sulfonyl]-
N-(p-toluenesulfonyl)-5-methyl-delta(2)-pyrazoline-1-carbamideGlipalamide [INN]Glipolamide; SPC 703Glipalamidum [INN-Latin]UNII-W7J490CUHMGlipalamida [INN-Spanish]GLIPALAMIDE [WHO-DD]SCHEMBL1816058

Database identifiers

CAS
37598-94-0
PubChem CID
65802
DTXSID
DTXSID80865876
ChEMBL
CHEMBL2105149
UNII
W7J490CUHM
Nikkaji
J395.236C

Properties

Computed structural properties

XLogP
1
Topological polar surface area
87.2 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
4
Rotatable bonds
2
Heavy atoms
19
Formal charge
0
Complexity
461

Physicochemical properties

FDA UNII
7 J490CUHM · W7J490CUHM

Chemistry & industry

Suppliers1 total

杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]

Related reactions

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Compound notes

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On this pageBasic informationOverviewNames & identifiersPropertiesChemistry & industryRelated reactionsCompound notes