Basic information
- CAS
128470-15-5- Standard SMILES
NCCS[As](SCCN)c1ccc(Nc2nc(N)nc(N)n2)cc1- InChIKey
MGEOLZFMLHYCFZ-UHFFFAOYSA-N- Molecular formula
- C13H21AsN8S2
- Average molar mass
- 428.4 g/mol
- Monoisotopic mass
- 428.054655
Overview
Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.
Names & identifiers
- Preferred name
- Melarsomine
- IUPAC
- 2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine
- English name
- Melarsomine
- Molecular formula
- C13H21AsN8S2
- Molecular weight
- 428.41
Names & synonyms
Melarsomine128470-15-5MelarsominaMelarsominum374GJ0S41ABis(2-aminoethyl) p-((4,6-diamino-s-triazin-2-yl)amino)dithiobenzenearsoniteDTXSID40155907Arsonodithious acid, as-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-, bis(2-aminoethyl) esterRM-340RefChem:58136DTXCID8078398Melarsomine [INN]
Show more names
bis(2-aminoethyl)(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)arsonodithioiteArsonodithious acid, As-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-, bis(2-aminoethyl) ester
CymelarsenMelarsomine (INN)2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamineMelarsominum [INN-Latin]Melarsomina [INN-Spanish]C13H21AsN8S2UNII-374GJ0S41AMELARSAMIN
Database identifiers
- CAS
128470-15-5- PubChem CID
- 65962
- DTXSID
DTXSID40155907
Properties
Computed structural properties
- Topological polar surface area
- 205 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 9
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 330
Physicochemical properties
- Boiling point
- 678.1 · 678.1±65.0 °C(Predicted)
- pka
- 8.62 · 8.62±0.10(Predicted)
- FDA UNII
- 374 GJ0S41A · 374GJ0S41A
Chemistry & industry
Pharmacology
ATC CodeQP - Antiparasitic products, insecticides and repellents
Applications
UsesMelarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].
Suppliers7 total
LGM Pharma1-(800)-881-8210 · [email protected]
Abblis Chemicals LLC+1-832-373-8299 · [email protected]
上海昕凯医药科技有限公司21-619849051-1 18521059765 · [email protected]
湖北威德利化学科技有限公司027-83991130 18627774460 · [email protected]
上海智乾生物科技有限公司[email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
AFINE CHEMICALS LIMITED+86-571-85134551 +86-18958018566 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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