Basic information
- CAS
134377-69-8- Standard SMILES
COCCCNC(=O)c1ccnc(C(=O)NCCCOC)c1- InChIKey
HLSXICGBWKECLM-UHFFFAOYSA-N- Molecular formula
- C15H23N3O4
- Average molar mass
- 309.36 g/mol
- Monoisotopic mass
- 309.16885622
Overview
Safironil is a small molecule drug. The usage of the INN stem '-nil' in the name indicates that Safironil is a benzodiazepine receptor antagonist/agonist. Safironil has a monoisotopic molecular weight of 309.17 Da.
Names & identifiers
- Preferred name
- Safironil
- IUPAC
- 2-N,4-N-bis(3-methoxypropyl)pyridine-2,4-dicarboxamide
- English name
- Safironil
- Molecular formula
- C15H23N3O4
- Molecular weight
- 309.36
Names & synonyms
Safironil134377-69-8Hoe-277safironiloCK4M8AX1LNHOE277DTXSID60158677N,N'-Bis(3-methoxypropyl)-2,4-pyridinedicarboxamidesafironilumRefChem:180805DTXCID7081168Safironil [INN]
Show more names
Safironil, 10 mM in DMSO2,4-Pyridinedicarboxamide, N2,N4-bis(3-methoxypropyl)-
2-N,4-N-bis(3-methoxypropyl)pyridine-2,4-dicarboxamideN2,N4-BIS(3-METHOXYPROPYL)PYRIDINE-2,4-DICARBOXAMIDEUNII-CK4M8AX1LNSCHEMBL344153orb1741319CHEMBL2105464HLSXICGBWKECLM-UHFFFAOYSA-NTS-09481
Database identifiers
- CAS
134377-69-8- PubChem CID
- 65973
- DTXSID
DTXSID60158677- ChEMBL
CHEMBL2105464- UNII
- CK4M8AX1LN
- Nikkaji
- J550.717K
Properties
Computed structural properties
- XLogP
- 0.2
- Topological polar surface area
- 89.6 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 10
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 339
Physicochemical properties
- FDA UNII
- 4 M8AX1LN · CK4M8AX1LN
Chemistry & industry
Applications
UsesSafironil is an antifibrotic compound. Safironil is a competitive inhibitor of collagen protein synthesis. Safironil reduces liver fibrogenesis by inhibiting HSC activation[1][2].
Suppliers7 total
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
韶关市启程生物科技有限公司18122215013 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
济南思考化学有限公司0531-0000 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Related reactions
2 records
Compound notes
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