Basic information
- CAS
108579-67-5- Standard SMILES
COC(=O)Nc1nc2ccc(SC(C)C)cc2[nH]1- InChIKey
SXJIZQPZESTWLD-UHFFFAOYSA-N- Molecular formula
- C12H15N3O2S
- Average molar mass
- 265.33 g/mol
- Monoisotopic mass
- 265.0884979
Overview
N-[6-(propan-2-ylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester is a member of benzimidazoles and a carbamate ester.
Names & identifiers
- Preferred name
- Methiazole
- IUPAC
- methyl N-(6-propan-2-ylsulfanyl-1H-benzimidazol-2-yl)carbamate
- English name
- Albendazole BP Impurity L
- Molecular formula
- C12H15N3O2S
- Molecular weight
- 265.33
Names & synonyms
Methiazole108579-67-5DTXSID50424979RefChem:925574DTXCID70375813118-567-9Albendazole EP Impurity L74239-55-74TZ75BBX8Zmethyl N-(6-propan-2-ylsulfanyl-1H-benzimidazol-2-yl)carbamateUNII-4TZ75BBX8ZAlbendazole impurity L [EP]
Show more names
Albendazole BP Impurity LAlbendazole Impurity 15（Albendazole EP Impurity L）Methyl N-[5-[(propan-2-yl)sulfanyl]-1H-benzimidazole-2-yl]carbamateMethyl N [5-(propane-2-yl)sulfanyl]-1H-benzimidazol-2- yl] carbamateCarbamic acid, N-[6-[(1-methylethyl)thio]-1H-benzimidazol-2-yl]-, methyl esterL.?me th yl?N-[5-[(propa n-2-yl)sulf a nyl]-1h -b e nzi mi d a zol-2-yl]c a rb a ma te .
methyl (5-(isopropylthio)-1H-benzo[d]imidazol-2-yl)carbamateMethyl (6-(isopropylthio)-1H-benzo[d]imidazol-2-yl)carbamateMethyl-N-(5-[propan-2-yl)sulfanyl]-1H-benzimidazol-2-yl)carbamateMethyl N-(5-((propan-2-yl)sulfanyl)-1H-benzimidazol-2-yl)carbamateCarbamic acid, (5-((1-methylethyl)thio)-1H-benzimidazol-2-yl)-, methyl esterAlbendazole EP Impurity L;Prestwick-14D11Albendazole Impurity L
Properties
Computed structural properties
- XLogP
- 2.8
- Topological polar surface area
- 92.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 301
Physicochemical properties
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- form
- Solid
- color
- Off-White to Pale Brown
- FDA UNII
- 4 TZ75BBX8Z · 4TZ75BBX8Z
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Chemistry & industry
Applications
UsesMethyl-N-(5-[propan-2-yl)sulfanyl]-1H-benzimidazol-2-yl)carbamate is an impurity of Albendazole (A511610), which is an anthelmintic drug. Also, it is one of the screening drugs against Echinococcus granulosus cysts in mice and their biological activities.
Suppliers31 total
怀化元研达生物技术有限责任公司18711085600 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
怀化元研达生物技术有限责任公司18711085600; 18229999901 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
杭州云易国科生物科技有限公司18457506494 · [email protected]
常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]
TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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