AM404
Basic information
- CAS
183718-77-6- Standard SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)Nc1ccc(O)cc1- InChIKey
IJBZOOZRAXHERC-DOFZRALJSA-N- Molecular formula
- C26H37NO2
- Average molar mass
- 395.6 g/mol
- Monoisotopic mass
- 395.28242942
Overview
AM404 is an anilide.
Names & identifiers
- Preferred name
- AM404
- IUPAC
- (5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamide
- English name
- AM 404
- Molecular formula
- C26H37NO2
- Molecular weight
- 395.58
Names & synonyms
AM 404am404(5Z,8Z,11Z,14Z)-N-(4-hydroxyphenyl)icosa-5,8,11,14-tetraenamideRefChem:915628183718-77-6AM-404198022-70-7N-arachidonoylaminophenol5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-CHEMBL39878XVJ94H0U215,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-
Show more names
N-(4-HYDROXYPHENYL)-ARACHIDONAMIDEN-(4-HYDROXYPHENYL) ARACHIDONOYLAMIDEARACHIDONOYLAMIDE, N-(4-HYDROXYPHENYL)N-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRENAMIDEN-(4-HYDROXYPHENYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE(all-Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenaMide
N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamideSMR000449274SR-01000597390UNII-XVJ94H0U21MFCD03095721N-(4-Hydroxyphenyl)arachidonylamideN-(4-Hydroxyphenyl)-arachidonylamideN-(4-Hydroxyphenyl)arachidonoyl amide
Database identifiers
- CAS
183718-77-6- PubChem CID
- 6604822
- DTXSID
DTXSID60424985- ChEMBL
CHEMBL39878- ChEBI
CHEBI:197140- UNII
- XVJ94H0U21
- Nikkaji
- J790.918G
Properties
Computed structural properties
- XLogP
- 7.2
- Topological polar surface area
- 49.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 15
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 511
Physicochemical properties
- Boiling point
- 579.4 · 579.4±50.0 °C(Predicted)
- Density
- 1.007 · 1.007±0.06 g/cm3(Predicted)
- Flash point
- 14 °C · 14 °C
- storage temp.
- -20 °C · -20°C
- solubility
- 24 mg/mL · ethanol: 24 mg/mL Photosensitive solution.
- form
- solution
- pka
- 10.11 · 10.11±0.26(Predicted)
- color
- Colorless to light yellow
- InChIKey
- IJBZOOZRAXHERC-DOFZRALJSA-N
- SMILES
- CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)Nc1ccc(O)cc1
- FDA UNII
- 94 H0U21 · XVJ94H0U21
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 32 · NA.32
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- 225 · H225-H319
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 1
- ridadr
- UN 1170 3/PG 2
- risk_code
- 36/37/38-11
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS07
- hazard_code
- F
- safety_code
- 7-16
- Storage Class
- 3 - Flammable liquids
- Hazard statements
- H225-H319
- Hazard Classifications
- Eye Irrit. 2Flam. Liq. 2
- Precautionary statements
- P210-P305+P351+P338
Chemistry & industry
Applications
UsesIt is a metabolite of the well-known analgesic Paracetamol. ase (FAAH) in vivo.
UsesPotentiates the activity of endogenous anandamide by blocking its re-uptake into presynaptic membranes. AM404 selectively inhibits the carrier-mediated transport of anandamide without affecting anandamide hydrolysis.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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