Basic information
- Standard SMILES
CC1CNCCN1- InChIKey
JOMNTHCQHJPVAZ-UHFFFAOYSA-N- Molecular formula
- C5H12N2
- Average molar mass
- 100.16 g/mol
- Monoisotopic mass
- 100.10004838
Overview
structure in first source
Names & identifiers
- Preferred name
- 2-Methylpiperazine
- IUPAC
- 2-methylpiperazine
- English name
- 2-Methylpiperazine
- Molecular formula
- C5H12N2
- Molecular weight
- 100.16
Names & synonyms
2-Methylpiperazine109-07-9Piperazine, 2-methyl-2-methyl piperazineD0LWN1061PNSC-5277DTXSID10219002(s)-methyl piperazineRefChem:88369DTXCID901900203-644-2MFCD00005954
Show more names
MP2MPRZ2-methyl-piperazinPiperazine,2-methyl-2-Methylpiperazine>2-Methylpiperazine,98%2-Methylpiperazine ,99%2-Methylpiperazine, 97+%
2-METHYL-PIPERAZINE(+/-)-2-MethylpiperazineEINECS 203-644-2BRN 0383566UNII-D0LWN1061P2methylpiperazine2-methylpiperazin2-methypiperazine
Database identifiers
- CAS
109-07-9- PubChem CID
- 66057
- DTXSID
DTXSID1021900- UNII
- D0LWN1061P
- EC Number
- 203-644-2
- Nikkaji
- J68.144J
Properties
Computed structural properties
- XLogP
- -0.4
- Topological polar surface area
- 24.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 54
Physicochemical properties
- Melting point
- 61 · 61-63 °C (lit.)
- Boiling point
- 155 °C/763 · 155 °C/763 mmHg (lit.)
- Density
- 0.817 g/cm · 0.817 g/cm
- refractive index
- 1.4378 · 1.4378 (estimate)
- Flash point
- 149 °F · 149 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- 435 g/l · 435g/l
- pka
- 1 · pK1:5.62(+2);pK2:9.60(+1) (25°C)
- form
- Crystalline Powder, Crystals and/or Chunks
- color
- White to yellow
- PH
- 11 · 11-12 (50g/l, H2O)
- Water Solubility
- 78 g/100 · 78 g/100 mL (25 ºC)
- Sensitive
- Air Sensitive & Hygroscopic
- BRN
- 383566 · 383566
- Henry's Law Constant
- 5 · 5.0×103 mol/(m3Pa) at 25℃, Nguyen (2013)
- InChI
- 1S/C5H12N2/c1-5-4-6-2-3-7-5/h5-7H,2-4H2,1H3
- InChIKey
- JOMNTHCQHJPVAZ-UHFFFAOYSA-N
- SMILES
- CC1CNCCN1
- CAS DataBase Reference
- 109 · 109-07-9(CAS DataBase Reference)
- FDA UNII
- 0 LWN1061P · D0LWN1061P
- NIST Chemistry Reference
- 2 · Piperazine, 2-methyl-(109-07-9)
- EPA Substance Registry System
- 2 · Piperazine, 2-methyl- (109-07-9)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 2 · GHS02,GHS05
- Signal word
- Danger
- Hazard statements
- 228 · H228-H314
- Precautionary statements
- 210 · P210-P240-P260-P280-P303+P361+P353-P305+P351+P338
- PPE
- 3 · Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
- Hazard Codes
- F,Xi
- Risk Statements
- 11 · 11-36/37/38
- Safety Statements
- 16 · 16-26-36/37/39-36
- RIDADR
- 1325 · UN 1325 4.1/PG 2
- WGK Germany
- 2 · 2
- RTECS
- 1225020 · TM1225020
- F
- 10 · 10
- TSCA
- TSCA listed
- HazardClass
- 4.1 · 4.1
- PackingGroup
- III
- HS Code
- 29339900 · 29339900
- Storage Class
- 4.1 B · 4.1B - Flammable solid hazardous materials
- Hazard Classifications
- 1 Flam · Eye Dam. 1Flam. Sol. 1Skin Corr. 1B
- REACH Registrations
- Active
- Limited Quantities
- 1 Kg · 1.0 Kg (2.2 lbs)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Safety & regulation
GHS classification
GHS Classification
Danger
H228 (99.4%): Flammable solid [Danger Flammable solids]
P210, P240, P241, P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 154 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationStatus: Active Update: 10-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19024
Hazard Classes and CategoriesFlam. Sol. 1 (99.4%)
Safety data
- F
- 10
- PPE
- Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 2
- tsca
- TSCA listed
- rtecs
- TM1225020
- ridadr
- UN 1325 4.1/PG 2
- hs_code
- 29339900
- risk_code
- 11-36/37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS05
- hazard_code
- F,Xi
- safety_code
- 16-26-36/37/39-36
- hazard_class
- 4.1
- Storage Class
- 4.1B - Flammable solid hazardous materials
- packing_group
- III
- Hazard statements
- H228-H314
- Limited Quantities
- 1.0 Kg (2.2 lbs)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
- REACH Registrations
- Active
- Hazard Classifications
- Eye Dam. 1Flam. Sol. 1Skin Corr. 1B
- Precautionary statements
- P210-P240-P260-P280-P303+P361+P353-P305+P351+P338
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationPiperazine, 2-methyl-: ACTIVE
Applications
Uses2-Methylpiperazine is used as a reagent in the design, synthesis and biological evaluation of diaminoquinazolines as b-catenine/Tcell transcription factor 4 (Tcf4) pathway inhibitor.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
上海德默医药科技有限公司400-021-7337 2355568890 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
嘉兴市艾森化工有限公司0573-85285100 18627885956 · [email protected]
Pure Chemistry Scientific Inc.001-857-928-2050 or 1-888-588-9418 · [email protected]
孝感深远化工有限公司15527621225; 15527621225 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
艾科试剂4008-755-333 18080918076 · [email protected]
上海思域化工科技有限公司86-21-34053660 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
上海健超生物科技有限公司150-2103-5486 18017383231 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
上海贤鼎生物科技有限公司4009209199 · [email protected]
深圳康特腾科技有限公司86-0755-86635001 · [email protected]
上海睿升化工科技有限公司+86-021-50935922
无锡中坤生化科技有限公司+86 0510-85629785
上海汇凯化学科技有限公司021-61995394 18916691159 · [email protected]
北京环宇世纪化学科技有限公司hysj_bj.com
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
上海将来实业股份有限公司021-61552785 · [email protected]
安徽科迪达化工有限公司0554-2106669 · [email protected]
日照力德士化工有限公司010-51268198 · [email protected]
美岚实业（上海）有限公司021-58958189 · [email protected]
上海爱蝶实业有限公司021-58957966 18930537195 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
广拓化学（上海）有限公司021-60899189-8001 18918189673 · [email protected]
雷丁试剂0510-85629785 18013409632 · [email protected]
上海御略医药科技有限公司021-60345187 13671753212 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海洽凡生化科技有限公司+86-021-61654350 · [email protected]
上海嵩爰化工科技有限公司010-1234567 18521000990 · [email protected]
上海有朋化工有限公司021-69005955 13701776567 · [email protected]
上海凯赛化工有限公司021-33516722 13701817765 · [email protected]
上海彤源化工有限公司021-021-69182866 13701855675 · [email protected]
Related reactions
301 records
Linked notes
Loading…