Trimethylsilanol

HCID 66110
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
1066-40-6
Standard SMILES
C[Si](C)(C)O
InChIKey
AAPLIUHOKVUFCC-UHFFFAOYSA-N
Molecular formula
C3H10OSi
Average molar mass
90.2 g/mol
Monoisotopic mass
90.05009147

Overview

RN given refers to parent cpd

Names & identifiers

Preferred name
Trimethylsilanol
IUPAC
hydroxy(trimethyl)silane
English name
hydroxytrimethylsilane
Molecular formula
C3H10OSi
Molecular weight
90.2

Names & synonyms

Trimethylsilanol1066-40-6HydroxytrimethylsilaneSilanol, trimethyl-TrimethylhydroxysilaneSilanol, 1,1,1-trimethyl-Z4BIN3300PDTXSID7061433RefChem:191810DTXCID3033010213-914-1hydroxy(trimethyl)silane
Show more names
TMSOHDK031LS 310SilanoleTrimethylsilanol,95%
C3H10OSiMFCD02751657CCRIS 1320EINECS 213-914-1UNII-Z4BIN3300PTrimethylsilanotrimethyl silanoltrimethyl-silanol

Database identifiers

CAS
1066-40-6
PubChem CID
66110
DTXSID
DTXSID7061433
ChEMBL
CHEMBL4238997
UNII
Z4BIN3300P
EC Number
213-914-1
Nikkaji
J555J

Properties

Computed structural properties

Topological polar surface area
20.2 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
1
Rotatable bonds
0
Heavy atoms
5

Experimental & physicochemical properties

Chemical ClassesMetals -> Metalloid Compounds (Silicon)
SpringerMaterials Properties29Si nuclear magnetic resonance spectrum
Vapor Pressure0.14 [mmHg]
Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)
Physical DescriptionColorless liquid with a strong odor; [Wacker Silicones MSDS]

Physicochemical properties

Melting point
-4.5 °C · -4.5 °C
Boiling point
90 ℃/760Torr · 90℃/760Torr
Density
0.95 · 0.950
vapor pressure
19 · 19-55hPa at 25℃
refractive index
1.3889 · 1.3889
Flash point
4 ° · 4°(39°F)

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 2.2% (5 of 232) of reports.

Danger

H225 (97.8%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P317, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 232 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Not Classified

Hazard information

Regulatory Information · 4 items

Chemical: Silanol, trimethyl-

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 02-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23873

Silanol, trimethyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards Summary · 1 item

Reduced spontaneous motor activity, staggering gait, and decreased body weight observed in 28-day oral study of rats at the highest tested dose (640 mg/kg/day); No evidence of mutagenicity; [JECDB] Contains 10-30% hexamethyl disiloxane (CAS# 107-46-0) as an impurity; May cause mild eye irritation; [Wacker Silicones MSDS] See Hexamethyldisiloxane and Dimethylsilane.

Hazard Classes and Categories · 2 items

Flam. Liq. 2 (97.8%)

Flammable liquids - Category 2

Safety & protection

Protective Action Criteria (PAC) · 3 items

2.1 [ppm]

23 [ppm]

140 [ppm]

Toxicology

Adverse EffectsNeurotoxin - Other CNS neurotoxin

Safety data

wgk
1
tsca
TSCA listed
ridadr
UN 1993BF 3 / PGII
hs_code
29319090
risk_code
11
Signal word
Danger

Chemistry & industry

Uses & manufacturing

UsesUsed as a chemical intermediate; [Wacker Silicones MSDS]
General Manufacturing InformationSilanol, 1,1,1-trimethyl-: ACTIVE
Applications · 2 items

DescriptionTrimethylsilanol has strong acidity compared with the corresponding carbon alcohols, can react with tetrahydrolithium aluminum, Si-OH bond can be reduced Si-H bond, can be used as a blocking agent for straight-chain polysiloxanes with hydrophobicity, it is the most important intermediate in the preparation of organosilicon alcohol salts and all kinds of polysiloxanes products including silicone oils, silicone rubbers and silicone resins, etc, and it has a wide range of application prospects.

UsesTrimethylsilanol used as a hydrophobic coat on silicate surfaces. Used as an as an antimicrobial agent.

Upstream & downstream products

Downstream products

Suppliers100 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]

Related reactions

3 records
New reaction record

Compound notes

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