Cyclooctasulfur

HCID 66348
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Basic information

CAS
10544-50-0
Standard SMILES
S1SSSSSSS1
InChIKey
JLQNHALFVCURHW-UHFFFAOYSA-N
Molecular formula
S8
Average molar mass
256.5 g/mol
Monoisotopic mass
255.776568

Overview

Cyclooctasulfur is a homomonocyclic compound composed of eight sulfur atoms. It has been isolated from Ganoderma lucidum, a mushroom commonly used in Chinese medicine. It has a role as a fungal metabolite and a bacterial metabolite. It is an elemental sulfur and a homomonocyclic compound.

Names & identifiers

Preferred name
Cyclooctasulfur
IUPAC
octathiocane
English name
Cyclic octaatomic sulfur
Molecular formula
S8
Molecular weight
256.52

Names & synonyms

OctathiocaneCyclooctasulfurOctasulfur10544-50-0CHEBI:29385DTXSID80872924RefChem:129811DTXCID60820468Cyclic octaatomic sulfurSulphur yellow 2Sulfur, mol. (S8)Cyclooctasulfane
Show more names
Sulfur,mol.(S8)Orthorhombic sulfuroctathiocycloctylalkane3,3'-(selenodithio)dipropionic acid
Sulfur S8HeliosoufreMicrosulfoSulfur powder70FD1KFU70SchwefelblumCosavetDelmite

Database identifiers

CAS
10544-50-0
PubChem CID
66348
DTXSID
DTXSID80872924
ChEMBL
CHEMBL1235452
ChEBI
CHEBI:29385
UNII
70FD1KFU70
EC Number
185-150-6、927-196-9
Nikkaji
J103.360C

Properties

Computed structural properties

XLogP
3.5
Topological polar surface area
202 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
8
Rotatable bonds
0
Heavy atoms
8

Experimental & physicochemical properties

SpringerMaterials PropertiesGibbs energy

Physicochemical properties

Density
1.862 · 1.862±0.06 g/cm3(Predicted)
FDA UNII
70 FD1KFU70 · 70FD1KFU70
EPA Substance Registry System
Octasulfur (10544-50-0)
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H228 (100%): Flammable solid [Danger Flammable solids]

P210, P240, P241, P264, P280, P302+P352, P321, P332+P317, P362+P364, and P370+P378 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesFlam. Sol. 2 (100%)

Safety data

Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H302-H315-H319-H335
Precautionary statements
P280-P305+P351+P338

Chemistry & industry

Pharmacology

Protein BindingIntended for local use only, no systemic absorption.
PharmacodynamicsSulfur is converted to hydrogen sulfide (H2S) through reduction, partly by bacteria. H2S has a lethal action on bacteria (possibly including Propionibacterium acnes) which plays a role in acne, fungi, and parasites such as scabies mites.
Mechanism of Action · 1 item

Sulfur acts as a keratolytic agent and also it has antibacterial activity. It also kills fungi, scabies mites and other parasites. Precipitated sulfur and colloidal sulfur are used, in form of lotions, creams, powders, soaps, and bath additives, for the treatment of acne vulgaris, acne rosacea, and seborrhoeic dermatitis.

Biological Half-LifeIntended for local use only, no systemic absorption.
Metabolism/MetabolitesIntended for local use only, no systemic absorption.
Absorption, Distribution and Excretion · 4 items

Intended for local use only, no systemic absorption.

Intended for local use only, no systemic absorption.

Intended for local use only, no systemic absorption.

Intended for local use only, no systemic absorption.

Applications

UsesCyclic octaatomic sulfur is a yellow, tasteless and odorless solid, commonly used as a comparative analytical substance for pickled egg products.

Upstream & downstream products

Suppliers17 total

陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Hebei baicao biology science and technology co., ltd+86-19131911055 17824879454 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
Compound Net Biotechnology Inc.15266686121 · [email protected]

Additional notes

DefinitionChEBI: A homomonocyclic compound composed of eight sulfur atoms. It has been isolated from Ganoderma lucidum, a mushroom commonly used in Chinese medicine.

Related reactions

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Compound notes

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