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Basic information
- CAS
13071-11-9- Standard SMILES
CC(C)NC[C@@H](O)COc1cccc2ccccc12.Cl- InChIKey
ZMRUPTIKESYGQW-PFEQFJNWSA-N- Molecular formula
- C16H22ClNO2
- Average molar mass
- 295.8 g/mol
- Monoisotopic mass
- 295.1339066
Names & identifiers
- Preferred name
- Dexpropranolol Hydrochloride
- IUPAC
- (2R)-1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride
- English name
- (R)-(+)-Propranolol
- Molecular formula
- C16H21NO2.ClH
- Molecular weight
- 295.81
Names & synonyms
13071-11-9Dexpropranolol hydrochlorideDexpropranolol HClI.C.I. 47,319AB9DB0NX46(+)-PROPRANOLOL HYDROCHLORIDEPropranolol hydrochloride, (r)-AY-20,694d-Propranolol hydrochlorideICI-47319NSC-757295AY 20694
Show more names
R-PROPRANOLOL(R)-(+)-PROPRANOLOL HYDROCHLORIDEICI 47319R-PROPANOLOLd-Anapriline(+)-Anapriline(R)-(+)-PropranololR-(+)-PROPANOLOL HCLexpropranololhydrochloride
AY-20694DTXSID30873365(+)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochlorideCHEBI:51161RefChem:585866DTXCID50820876AY20694235-961-7
Database identifiers
- CAS
13071-11-9- PubChem CID
- 66366
- DTXSID
DTXSID30873365- ChEMBL
CHEMBL1358662- UNII
- AB9DB0NX46
- EC Number
- 235-961-7
Properties
Computed structural propertiesFilling in
- Topological polar surface area
- 41.5 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 6
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 257
Physicochemical properties
- Melting point
- 196 · 196-198 °C(lit.)
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 10 mg/mL · ethanol: 10 mg/mL
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 100 mM · Soluble to 100 mM in water
- BRN
- 5780490 · 5780490
- CAS DataBase Reference
- 13071 · 13071-11-9(CAS DataBase Reference)
- FDA UNII
- 9 DB0NX46 · AB9DB0NX46
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P501
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22
- Safety Statements
- 22 · 22-24/25
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- hs_code
- 2922 19 00
- risk_code
- 22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 22-24/25
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
Chemistry & industry
Applications
Description(R)-Propranolol hydrochloride is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist with high affinity for β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.
Usesless active enantiomer
UsesThe R-enantiomer of Propranolol (P831800). βAdrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
Suppliers61 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
武汉易泰科技有限公司上海分公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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