Basic information
- CAS
129-24-8- Standard SMILES
O=c1[nH]c2ccccc2c(-c2ccccc2)c1O- InChIKey
QSRVMXWVVMILDI-UHFFFAOYSA-N- Molecular formula
- C15H11NO2
- Average molar mass
- 237.25 g/mol
- Monoisotopic mass
- 237.07897859
Overview
Viridicatin is a hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae. It has a role as an antibacterial agent, a marine metabolite, an Aspergillus metabolite and a Penicillium metabolite. It is a conjugate acid of a viridicatin(1-).
Names & identifiers
- Preferred name
- Viridicatin
- IUPAC
- 3-hydroxy-4-phenyl-1H-quinolin-2-one
- English name
- viridicatin
- Molecular formula
- C15H11NO2
- Molecular weight
- 237.25
Names & synonyms
Viridicatin129-24-83-hydroxy-4-phenyl-1H-quinolin-2-one2,3-dihydroxy-4-phenylquinoline3-Hydroxy-4-phenyl-2(1H)-quinolinone45493KS618CHEBI:140443DTXSID10156022RefChem:194446DTXCID70785133-hydroxy-4-phenylquinolin-2(1H)-one3-Hydroxy-4-phenyl-1,2-dihydroquinolin-2-one
Show more names
2(1H)-Quinolinone, 3-hydroxy-4-phenyl-
multiplolides IUNII-45493KS618VIRIDICATIN [MI]orb1692101SCHEMBL5396117CHEMBL2386742SCHEMBL29709937ACon0_001468
Database identifiers
- CAS
129-24-8- PubChem CID
- 67206
- DTXSID
DTXSID10156022- ChEMBL
CHEMBL2386742- ChEBI
CHEBI:140443- UNII
- 45493KS618
- Nikkaji
- J5.422D
Properties
Computed structural properties
- XLogP
- 2.4
- Topological polar surface area
- 49.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 369
Physicochemical properties
- Melting point
- 268 ° · 268°
- storage temp.
- -20 °C · Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: moderately soluble; Methanol: moderately soluble
- form
- Off-white to brown solid.
- FDA UNII
- 45493 KS618 · 45493KS618
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 303 · H303-H313-H320-H333
- Precautionary statements
- 261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H303-H313-H320-H333
- Precautionary statements
- P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Chemistry & industry
Applications
UsesViridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the benzodiazepine, cyclopenin. Viridicatin exhibits potent selective activity against Mycobacterium tuberculosis, but is inactive against most other bacteria.
UsesViridicatin is aPenicilliummetabolite active againstMycobacterium tuberculosis. Isolated from deep-sea Penicillium griseofulvum alleviates anaphylaxis and has anti-allergic properties.
Suppliers18 total
西安瑞禧生物科技有限公司7895 17778953996 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
桂林艾使普林生物科技有限公司15920419256 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
西安强化生物科技有限公司15339237155 15339237155 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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