N,N'-diacetyl-p-phenylenediamine
Basic information
- CAS
140-50-1- Standard SMILES
CC(=O)Nc1ccc(NC(C)=O)cc1- InChIKey
KVEDKKLZCJBVNP-UHFFFAOYSA-N- Molecular formula
- C10H12N2O2
- Average molar mass
- 192.21 g/mol
- Monoisotopic mass
- 192.08987763
Overview
promotes phagocytosis by microglia, improving cognitive deficits associated with Alzheimer's disease in mouse model
Names & identifiers
- Preferred name
- N,N'-diacetyl-p-phenylenediamine
- IUPAC
- N-(4-acetamidophenyl)acetamide
- English name
- N,N'-DIACETYL-1,4-PHENYLENEDIAMINE
- Molecular formula
- C10H12N2O2
- Molecular weight
- 192.21
Names & synonyms
140-50-1N,N'-Diacetyl-1,4-phenylenediamineAcetamide, N,N'-1,4-phenylenebis-1,4-BisacetamidobenzeneN,N'-Diacetyl-p-phenylenediaminep-Phenylenediacetamide4'-AcetamidoacetanilideAcetamide, N,N'-p-phenylenebis-I96A01798WNSC-401116DTXSID2059695DAPPD
Show more names
TIMTEC-BB SBB006302p-DiacetamidobenzeneN,N'-DIACETYLPHENYLENEDIAMINEN,N'-1,4-phenylenediacetamide
RefChem:821878DTXCID7034541205-417-31,4-DiacetamidobenzeneN-(4-acetamidophenyl)acetamideN,N'-p-PhenylenebisacetamideN,N'-(1,4-Phenylene)diacetamideN,N'-1,4-Phenylenebisacetamide
Database identifiers
- CAS
140-50-1- PubChem CID
- 67324
- DTXSID
DTXSID2059695- UNII
- I96A01798W
- EC Number
- 205-417-3
- Nikkaji
- J79.459G
Properties
Computed structural properties
- XLogP
- 0.8
- Topological polar surface area
- 58.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 196
Physicochemical properties
- Melting point
- 300 °C · >300°C
- Boiling point
- 483.8 · 483.8±28.0 °C(Predicted)
- Density
- 1.235 · 1.235±0.06 g/cm3(Predicted)
- RTECS
- 7709500 · AC7709500
- pka
- 14.29 · 14.29±0.70(Predicted)
- form
- powder to crystaline
- color
- White to Green to Brown
- BRN
- 2806271 · 2806271
- CAS DataBase Reference
- 140 · 140-50-1(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 96 A01798W · I96A01798W
- EPA Substance Registry System
- -1 · Acetamide, N,N'-1,4-phenylenebis- (140-50-1)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 335 · H335-H315-H319
- Precautionary statements
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- tsca
- TSCA listed
- ridadr
- 2811
- hs_code
- 2924297099
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 26-36/37/39
- hazard_class
- 6.1
- packing_group
- III
- Hazard statements
- H335-H315-H319
- Precautionary statements
- P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Uses & manufacturing
General Manufacturing InformationAcetamide, N,N'-1,4-phenylenebis-: INACTIVE
Suppliers
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Related reactions
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Compound notes
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