Basic information
- CAS
142-48-3- Standard SMILES
CCCCCCCCCCCCCCCCCC(=O)N(C)CC(=O)O- InChIKey
RJYOKYDKKOFLBT-UHFFFAOYSA-N- Molecular formula
- C21H41NO3
- Average molar mass
- 355.6 g/mol
- Monoisotopic mass
- 355.30864417
Overview
The CIR Expert Panel concluded that the following ingredients are safe as used in cosmetics when formulated to be non-irritating. The Expert Panel cautions that these ingredients should not be used in cosmetic products in which N-nitroso compounds can be found...Stearoyl Sarcosine...
Names & identifiers
- Preferred name
- Stearoyl Sarcosine
- IUPAC
- 2-[methyl(octadecanoyl)amino]acetic acid
- English name
- STEAROYL SARCOSINE
- Molecular formula
- C21H41NO3
- Molecular weight
- 355.56
Names & synonyms
Stearoyl sarcosine142-48-3n-stearoylsarcosineGlycine, N-methyl-N-(1-oxooctadecyl)-UNII-AJ0EI4K4R8AJ0EI4K4R8SARKOSYL SStearoyl N-methylaminoacetic acidStearoyl N-methylglycineEINECS 205-539-7SARCOSINE, N-STEAROYL-N-OCTADECANOYL-SARCOSINE
Show more names
Stearoyl SarcosinN-OctadecanoylsarcosineN-(1-Oxooctadecyl)sarkosinN-(1-oxooctadecyl)sarcosineN-Octadecanoyl-N-methylglycine2-(N-Methylstearamido)acetic acidn-methyl-n-(1-oxooctadecyl)-glycin
DTXSID8059716N-Methyl-N-(1-oxooctadecyl)glycine(N-METHYL-N-OCTADECANOYLAMINO)ACETIC ACIDRefChem:185410DTXCID4034609STEAROYL SARCOSINE [INCI]205-539-7n-methyl-n-stearoylglycine
Database identifiers
- CAS
142-48-3- PubChem CID
- 67339
- DTXSID
DTXSID8059716
Properties
Computed structural properties
- XLogP
- 7.7
- Topological polar surface area
- 57.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 18
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 331
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Stearoyl Sarcosine) -> CIR (Cosmetic Ingredient Review)
Surfactant; Hair conditioning; Antistatic
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physicochemical properties
- Melting point
- 65 · 65-66.5 °C
- Boiling point
- 489.8 · 489.8±28.0 °C(Predicted)
- Density
- 0.95 · 0.950±0.06 g/cm3(Predicted)
- pka
- 3.62 · 3.62±0.10(Predicted)
- Cosmetics Ingredients Functions
- HAIR CONDITIONINGSURFACTANT - CLEANSINGCLEANSINGANTISTATIC
- LogP
- 7.294 · 7.294 (est)
- Indirect Additives used in Food Contact Substances
- N-STEAROYLSARCOSINE
- FDA 21 CFR
- 177.12 · 177.1200
- EWG's Food Scores
- 1 · 1-2
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)
Aggregated GHS information provided per 18 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: Glycine, N-methyl-N-(1-oxooctadecyl)-
Glycine, N-methyl-N-(1-oxooctadecyl)-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesEye Dam. 1 (100%)
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the following ingredients are safe as used in cosmetics when formulated to be non-irritating. The Expert Panel cautions that these ingredients should not be used in cosmetic products in which N-nitroso compounds can be found...Stearoyl Sarcosine...
Safe for use in cosmetics, with qualifications
Safety data
- tsca
- TSCA listed
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Stearoyl Sarcosine
Use ClassificationCosmetics -> Surfactant; Hair conditioning; Antistatic
General Manufacturing InformationGlycine, N-methyl-N-(1-oxooctadecyl)-: ACTIVE
Suppliers29 total
北京华美互利生物化工010-56205725 · [email protected]
陕西格列弗生物科技研究有限责任公司18409274651; 13892423764 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
郑州汇聚化工有限公司13393710386 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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