CAS 144-79-6 Chloro(methyl)diphenylsilane (HCID 67349)

Names & identifiers

Preferred name: Chloro(methyl)diphenylsilane
IUPAC: chloro-methyl-diphenylsilane
English name: Chlorodiphenylmethylsilane
Molecular formula: C13H13ClSi
Molecular weight: 232.78

Names & synonyms

Chloro(methyl)diphenylsilane144-79-6DiphenylmethylchlorosilaneChloromethyldiphenylsilaneDTXSID3027116DTXCID607116CMDPSRefChem:125448205-639-0MethyldiphenylchlorosilaneChlorodiphenylmethylsilaneSilane, chloromethyldiphenyl-

Show more names

diphenylmethylsilyl chlorideDK077DK542DPMSCIDKFELEX0133Diphenylmethylchlorodichloromethylchlorosilane

Methyldiphenylsilyl chlorideC13H13ClSichloro-methyl-diphenylsilaneChloro-methyl-diphenyl-silaneMFCD00000498DPMSClS07950EINECS 205-639-0

Database identifiers

CAS: 144-79-6
PubChem CID: 67349
DTXSID: DTXSID3027116
ChEMBL: CHEMBL3182736
EC Number: 205-639-0
Nikkaji: J109.082H

Properties

Computed structural properties

Topological polar surface area: 0 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 0
Rotatable bonds: 2
Heavy atoms: 15
Formal charge: 0
Complexity: 175

Experimental & physicochemical properties

Physical DescriptionLiquid

Kovats Retention Index · 2 items

1675.2

1675.5

Physicochemical properties

Melting point: -22 °C · -22°C
Boiling point: 295 °C · 295 °C (lit.)
Density: 1.107 g/mL · 1.107 g/mL at 25 °C (lit.)
vapor pressure: 3 mm · 3 mm Hg ( 125 °C)
refractive index: 20 · n20/D 1.574(lit.)
Flash point: 230 °F · >230 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: sol most organic solvents; reacts with protic solvents such as alcohols, acids, amines, water.
form: clear liquid
color: Colorless to Light yellow to Light orange
Specific Gravity: 1.128 · 1.128
Water Solubility: reacts
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 8 · 8: reacts rapidly with moisture, water, protic solvents
BRN: 2937445 · 2937445
InChI: 1S/C13H13ClSi/c1-15(14,12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3
InChIKey: OJZNZOXALZKPEA-UHFFFAOYSA-N
SMILES: C[Si](Cl)(c1ccccc1)c2ccccc2
CAS DataBase Reference: 144 · 144-79-6(CAS DataBase Reference)
NIST Chemistry Reference: Silane, chloromethyldiphenyl-(144-79-6)
EPA Substance Registry System: Silane, chloromethyldiphenyl- (144-79-6)
UNSPSC Code: 12352002 · 12352002
NACRES: 22 · NA.22
Symbol(GHS): 5 · GHS05
Signal word: Danger
Hazard statements: 314 · H314
Precautionary statements: 280 · P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 34 · 34-37
Safety Statements: 26 · 26-36/37/39-45-25
RIDADR: 2987 · UN 2987 8/PG 2
WGK Germany: 1 · 1
F: 10 · 10-21
TSCA: TSCA listed
HazardClass: 8 · 8
PackingGroup: II
HS Code: 29319090 · 29319090
Storage Class: 8 A · 8A - Combustible corrosive hazardous materials
Hazard Classifications: 1 Skin · Eye Dam. 1Skin Corr. 1B
Excepted Quantities: Not Permitted as Excepted Quantity

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 44 reports by companies from 3 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 2 items

Chemical: Silane, chloromethyldiphenyl-

Benzene, 1,1'-(chloromethylsilylene)bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzene, 1,1'-(chloromethylsilylene)bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Hazard Classes and CategoriesSkin Corr. 1B (100%)

Regulatory information

Regulatory Information · 2 items

Chemical: Silane, chloromethyldiphenyl-

Benzene, 1,1'-(chloromethylsilylene)bis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzene, 1,1'-(chloromethylsilylene)bis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Safety data

F: 10-21
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 1
tsca: TSCA listed
ridadr: UN 2987 8/PG 2
hs_code: 29319090
risk_code: 34-37
Signal word: Danger
Symbol(GHS): GHS05
hazard_code: C
safety_code: 26-36/37/39-45-25
hazard_class: 8
Storage Class: 8A - Combustible corrosive hazardous materials
packing_group: II
Hazard statements: H314
Excepted Quantities: Not Permitted as Excepted Quantity
Hazard Classifications: Eye Dam. 1Skin Corr. 1B
Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Chemistry & industry

Uses & manufacturing

U.S. Production2023: 250,000 - <550,000 lb；2022: 50,000 - <250,000 lb；2021: 50,000 - <250,000 lb；2020: 50,000 - <250,000 lb

Industry UsesMonomers

General Manufacturing Information · 2 items

All Other Basic Inorganic Chemical Manufacturing

Benzene, 1,1'-(chloromethylsilylene)bis-: ACTIVE

Applications · 3 items

UsesUsed in the pharmaceutical and chemical industry.

UsesMethyldiphenylchlorosilane can be used as protecting group for alcohols; reacts with carboxylic acids and sulfoximes; C-silylates lithium ester enolates.

UsesChloro(methyl)diphenylsilane is used in agrochemical, pharmaceutical and dyestuff field .

Preparation methods

PreparationChlorodiphenylmethylsilane was prepared by Grignard reaction under mild reaction conditions using bromobenzene, methylphenyldichlorosilane, and magnesium as raw materials.