Basic information
- CAS
138-92-1- Standard SMILES
Cl.Cl.NCCc1ccn[nH]1- InChIKey
BUXCUOWXTOKEMQ-UHFFFAOYSA-N- Molecular formula
- C5H11Cl2N3
- Average molar mass
- 184.06 g/mol
- Monoisotopic mass
- 183.0330028
Overview
Betazole dihydrochloride is the dihydrochloride salt of betazole. It has a role as a diagnostic agent, a histamine agonist and a gastrointestinal drug. It is a member of pyrazoles and a hydrochloride. It contains a betazole.
Names & identifiers
- Preferred name
- Betazole Dihydrochloride
- IUPAC
- 2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride
- English name
- Betazole hydrochloride
- Molecular formula
- C5H11Cl2N3
- Molecular weight
- 184.06694
Names & synonyms
Betazole dihydrochlorideAmetazole dihydrochloride3-beta-Aminoethylpyrazole dihydrochloride2-(3-Pyrazolyl)ethylamine dihydrochlorideRefChem:57949205-345-2138-92-1Betazole hydrochloride2-(3-Pyrazolyl)ethanamine dihydrochlorideHistalog1h-pyrazole-3-ethanamine dihydrochlorideBetazole HCl
Show more names
HistimingastramineHistalog (TN)Betazole 2HClbetazolehydrochloridebetazoledihydrochloride2-(3-Pyrazolyl)ethylaminametazoledihydrochlorideBetazole hydrochloride (JAN)
Betazole (dihydrochloride)3-(2-Aminoethyl)pyrazole dihydrochlorideMFCD016937041H-Pyrazole-3-ethanamine, dihydrochloride2-(1H-pyrazol-3-yl)ethanamine dihydrochloride2-(1H-Pyrazol-3-yl)-ethylamine dihydrochloride66ABP6C83F2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride
Database identifiers
- CAS
138-92-1- PubChem CID
- 67412
- ChEMBL
CHEMBL1200949、CHEMBL4303510- ChEBI
CHEBI:31280- UNII
- 66ABP6C83F
- EC Number
- 205-345-2
Properties
Computed structural properties
- Topological polar surface area
- 54.7 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 64.7
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physicochemical properties
- Melting point
- 224 · 224-226°
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 37 mg/mL · DMSO: 37 mg/mL (201.01 mM);Ethanol: 18 mg/mL (97.79 mM)
- Water Solubility
- 37 mg/mL · Water: 37 mg/mL (201.01 mM)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 66 ABP6C83F · 66ABP6C83F
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280-P301+P312-P302+P352-P305+P351+P338
- HS Code
- 2933199090 · 2933199090
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- hs_code
- 2933199090
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.
Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically.
Applications
UsesBetazole Hydrochloride is a histamine H2 receptor agonist that is used as a gastric stimulant for the investigation of gastric secretion activity.
Upstream & downstream products
Upstream raw materials
Suppliers39 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海爱孜康医药研究有限公司18721109360 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
杰达维（上海）医药科技发展有限公司/J & W PharmLab021-64340559 · [email protected]
河南伊诺凯新材料有限公司15670530983 · [email protected]
湖北扬信医药科技有限公司0714-3999001 19171453112 · [email protected]
上海陶素生化科技有限公司021-33632979 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Chongqing jooe co., ltd+86-15223382610 · [email protected]
江苏倍达医药科技有限公司0512-63009836 18994340901 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
上海珞珐生化科技有限公司021-51111890 15317326293 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd+8613580539051 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海颖心实验室设备有限公司021-021-59178156 15300768757 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 13913916777 · [email protected]
北京珐默兹医药科技有限公司010-80339217; 13331045123 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
Accela ChemBio Inc.+1-858-6993322 +86-18019713315 · [email protected]
Aladdin Scientific[email protected]
上海康恩博医药科技有限公司（科小研试剂）400-1388-521 17510465506 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
南京康满林化工实业有限公司025-83697070 13770331960 · [email protected]
Jilin Chinese Academy of Sciences-yanshen Technology18143011203 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
上海鼓臣生物技术有限公司021-34675735 19147740836 · [email protected]
上海安毕达生物科技有限公司021-61629020 18201956406 · [email protected]
上海弘渠生物医药科技有限公司88888888888 · [email protected]
Additional notes
DefinitionChEBI: The dihydrochloride salt of betazole.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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