Basic information
- CAS
140-63-6- Standard SMILES
N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2)cc1.O=S(=O)(O)CCO.O=S(=O)(O)CCO- InChIKey
WSOSYBUSMXEYDO-UHFFFAOYSA-N- Molecular formula
- C21H32N4O10S2
- Average molar mass
- 564.6 g/mol
- Monoisotopic mass
- 564.15598558
Overview
Propamidine isethionate is a guanidinium salt obtained by combining propamidine with two molar equivalents of isethionic acid. Used for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. It has a role as an antimicrobial agent and an antiseptic drug. It is an organosulfonate salt and a guanidinium salt. It contains a propamidine(2+).
Names & identifiers
- Preferred name
- Propamidine isethionate
- IUPAC
- 4-[3-(4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide;bis(2-hydroxyethanesulfonic acid)
- English name
- propamidine isetionate
- Molecular formula
- C17H20N4O2.2C2H6O4S
- Molecular weight
- 564.62958
Names & synonyms
Propamidine isethionatePropamidine isetionate140-63-6M&B 782Golden eye dropsM + B 7827T9IJ84C42CHEBI:87175DTXSID50161211RefChem:176253DTXCID5083702205-423-6
Show more names
PROPAMIDINEISTHIONATE
Propamidine diisethionate4,4'-(Propane-1,3-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)Propamidine isthionate2-hydroxyethane-1-sulfonic acid--4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide) (2/1)EINECS 205-423-6UNII-7T9IJ84C42BROLENE DROPSPropamidine Diisetionate
Database identifiers
- CAS
140-63-6- PubChem CID
- 67413
- DTXSID
DTXSID50161211- ChEBI
CHEBI:87175- UNII
- 7T9IJ84C42
- EC Number
- 205-423-6
Properties
Computed structural properties
- Topological polar surface area
- 284 Ų
- Hydrogen bond donors
- 8
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 12
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 467
Physicochemical properties
- Melting point
- 235 ℃ · 235℃
- FDA UNII
- 7 T9IJ84C42 · 7T9IJ84C42
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319
- Precautionary statements
- 501 · P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS ClassificationNot Classified
Hazard information
Other Safety InformationIMAP assessments - Ethanesulfonic acid, 2-hydroxy-, compound with 4,4'-[1,3-propanediylbis(oxy)]bis[benzenecarboximidamide] (2:1): Environment tier I assessment
Hazard Classes and CategoriesNot Classified
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319
- Precautionary statements
- P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances that are destructive to protozoans.
Applications
UsesPropamidine (isethionate) is an agent in the diamidine class. Propamidine (isethionate) can be used in research of Acanthamoeba keratitis[1].
Suppliers10 total
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
江苏艾康生物医药研发有限公司025-5885952 15955137747 · [email protected]
湖北魏氏化学试剂股份有限公司17771898297 13125137661 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
天津凯利奇生物科技有限公司15076683720 · [email protected]
陕西缔都医药化工有限公司029-81154043 17391733319 · [email protected]
河南天孚化工有限公司+86-0371-55170693 +86-19937530512 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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