Basic information
- CAS
130-24-5- Standard SMILES
Cc1cc(N)c2ccccc2c1O- InChIKey
UGQFCTZXVAPVCS-UHFFFAOYSA-N- Molecular formula
- C11H11NO
- Average molar mass
- 173.21 g/mol
- Monoisotopic mass
- 173.08406397
Overview
4-Amino-2-methyl-1-naphthol is a member of naphthols.
Names & identifiers
- Preferred name
- Vitamin K5
- IUPAC
- 4-amino-2-methylnaphthalen-1-ol
- English name
- VITAMIN K5
- Molecular formula
- C11H11NO
- Molecular weight
- 173.21
Names & synonyms
Vitamin k54-amino-2-methylnaphthalen-1-ol4-Amino-2-methyl-1-naphthol83-70-5Synkamin4-Amino-2-methyl-1-naphthalenol1-Naphthalenol, 4-amino-2-methyl-1-NAPHTHOL, 4-AMINO-2-METHYL-KKP97T7O0XDTXSID30750424-Amino-2-methyl-1-naphthalenol, hydrochlorideRefChem:194540
Show more names
kayvisynsynkaminbase4-amino-2-methyl-1-naphtho2-methyl-4-amino-1-naphthol4-amino-2-methyl-1-naphthaleno4-Amino-2-methyl-1-naphthol hci
DTXCID6048337Synkamin base3-Methyl-4-hydroxy-1-naphthylamine1-Hydroxy-2-methyl-4-aminonaphthalene2-Methyl-4-amino-1-hydroxynaphthaleneSynkamin; Synkamin base89298-62-4CHEMBL5191355
Database identifiers
- CAS
130-24-5、83-70-5- PubChem CID
- 6754
- DTXSID
DTXSID3075042- ChEMBL
CHEMBL5191355- ChEBI
CHEBI:195927- UNII
- KKP97T7O0X
Properties
Computed structural properties
- XLogP
- 2.5
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 183
Physicochemical properties
- Boiling point
- 303.86 °C · 303.86°C (rough estimate)
- Density
- 1.0898 · 1.0898 (rough estimate)
- refractive index
- 1.495 · 1.4950 (estimate)
- storage temp.
- -20 · Store at -20
- pka
- 9.78 · 9.78±0.50(Predicted)
- FDA UNII
- 97 T7O0X · KKP97T7O0X
- EPA Substance Registry System
- 5 · Vitamin K5 (83-70-5)
Chemistry & industry
Pharmacology
Cellular LocationsCytoplasm
Applications
UsesVitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages[1][2][3].
Suppliers3 total
Alfa Chemistry+1-5166625404 · [email protected]
湖北玖天生物医药科技有限公司027-88013699 17354350817 · [email protected]
上海同田生物技术有限公司021-51320588 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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