Basic information
- CAS
353-09-3- Standard SMILES
NC(N)=NCCC(=O)O- InChIKey
KMXXSJLYVJEBHI-UHFFFAOYSA-N- Molecular formula
- C4H9N3O2
- Average molar mass
- 131.13 g/mol
- Monoisotopic mass
- 131.06947654
Overview
3-guanidinopropanoic acid is a guanidine compound bearing an N-(2-carboxyethyl) substituent. It is a creatine analogue that has been found to decreases plasma glucose levels. It has a role as a hypoglycemic agent. It is functionally related to a propionic acid. It is a tautomer of a 3-guanidinopropanoic acid zwitterion.
Names & identifiers
- Preferred name
- Beta-Guanidinopropionic acid
- IUPAC
- 3-(diaminomethylideneamino)propanoic acid
- English name
- 3-Guanidinopropionic acid
- Molecular formula
- C4H9N3O2
- Molecular weight
- 131.13
Names & synonyms
353-09-3beta-Guanidinopropionic acidOmpenaclidGuanidinopropionic acid3-carbamimidamidopropanoic acidbeta-GPAamidino beta-alanineN-(Aminoiminomethyl)-beta-alanineORISTAR GPAPNU-10483RGX202Rgx 202
Show more names
β-Guanidinopropionic acid3-GUANIDINOPROPIONIC ACID3-Guanidinopropanoate3-guanidinopropanoicacidRGX-202RGX-202 ，E1223beta-Guanidinopropio
UL1984YRKA3-[(diaminomethylidene)amino]propanoic acidDTXSID401887953-((diaminomethylidene)amino)propanoic acidbeta-guanidine propionic acidRefChem:782874SLC6A8 Inhibitor RGX-202DTXCID00111286
Database identifiers
- CAS
353-09-3- PubChem CID
- 67701
- DTXSID
DTXSID40188795- ChEMBL
CHEMBL20489- ChEBI
CHEBI:15968
Properties
Computed structural properties
- XLogP
- -1.8
- Topological polar surface area
- 102 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 128
Experimental & physicochemical properties
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 222 °C · 222 °C (dec.)(lit.)
- Boiling point
- 299.1 · 299.1±42.0 °C(Predicted)
- Density
- 1.46 · 1.46±0.1 g/cm3(Predicted)
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Aqueous Acid (Slightly), Water (Slightly, Heated)
- form
- Solid
- pka
- 4.22 · 4.22±0.10(Predicted)
- color
- White to Off-White
- BRN
- 1705262 · 1705262
- Cosmetics Ingredients Functions
- SKIN CONDITIONING
- InChI
- 1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)
- InChIKey
- KMXXSJLYVJEBHI-UHFFFAOYSA-N
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- rtecs
- AY3157500
- hs_code
- 29252900
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Applications
DescriptionGuanidinopropionic acid is a white crystal that dissolves in water and is a creatine analog. Guanidinopropionic acid is a kind of amino acid derivatives. It is an important chemical raw material and intermediate. It exists in the serum, brain, liver, kidney and urine of mammals. It can improve insulin sensitivity and selectively reduce Adipose tissue weight can treat and prevent metabolic disorders, hyperglycemia, hyperinsulinemia, insensitivity to blood insulin, hyperlipidemia, hyperamylase, obesity and other symptoms.
Uses3-Guanidinopropionic Acid is an acidic guanidine derivative that has been shown to ameliorate hyperglycemia in animal models of noninsulin-dependent diabetes.
Suppliers100 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
衢州明锋化工有限公司0570-3062502 13819002126;13819008176 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
山东穗泰生物科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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