Basic information
- CAS
360-81-6- Standard SMILES
CC1=NS(=O)(=O)c2ccccc2N1- InChIKey
FDWRKMPNEIXNOE-UHFFFAOYSA-N- Molecular formula
- C8H8N2O2S
- Average molar mass
- 196.23 g/mol
- Monoisotopic mass
- 196.03064868
Names & identifiers
- Preferred name
- 2H-1,2,4-Benzothiadiazine, 3-methyl-, 1,1-dioxide
- IUPAC
- 3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
- English name
- 3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
- Molecular formula
- C8H8N2O2S
- Molecular weight
- 196.23
Names & synonyms
Mebetide360-81-62H-1,2,4-Benzothiadiazine, 3-methyl-, 1,1-dioxideDTXSID00189561RefChem:1064954DTXCID601120523-methyl-4h-1,2,4-benzothiadiazine 1,1-dioxide3-Methyl-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide3-Methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide3-methyl-4H-1lambda6,2,4-benzothiadiazine 1,1-dioxideHydrochlorothiazide Impurity 19CHEMBL1993421
Show more names
Desipramine Impurity 10Diazoxide Deschloro ImpurityDiazoxide impurity-1 (Deschloro diazoxide)3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide3-Methyl-4H-benzo[E][1,2,4]thiadiazine 1,1-dioxide
NSC-634166Deschloro Diazoxide3-Metil-2H-1,2,4-benzotiodiazina 1,1-diossido [Italian]FG4VNA7BBK3-Methyl-1,2,4-benzothiadiazine-1,1-dioxideDeschloro diazoxide impurityHydrochlorothiazide Impurity3-Metil-2H-1,2,4-benzotiodiazina 1,1-diossido
Database identifiers
- CAS
360-81-6
Properties
Computed structural properties
- XLogP
- 0.3
- Topological polar surface area
- 66.9 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 329
Experimental & physicochemical properties
LogP0.29
Physicochemical properties
- Melting point
- 264 · 264 - 267°C
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Major Application
- pharmaceutical small molecule
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 317 · H317
- Precautionary statements
- 261 · P261-P272-P280-P302+P352-P333+P313-P362+P364
- WGK Germany
- 3 · WGK 3
- Storage Class
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- WGK 3
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H317
- Hazard Classifications
- Skin Sens. 1A
- Precautionary statements
- P261-P272-P280-P302+P352-P333+P313-P362+P364
Chemistry & industry
Applications
Uses3-Methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide functions in structure activity relations analysis of benzothiadiazine compounds as hyperglycemic agents by correlating with the reduction in urine output in vivo and insulin production both in vivo and in vitro. Also functions as an antihypertensive agent.
Suppliers16 total
湖北瑞玛标物科技有限公司15787879035 15787875101 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
江苏艾康生物医药研发有限公司025-5885952 15955137747 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
上海笛柏生物科技有限公司400-008-9730,021-54359730 400-008-9730 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
南京熙泽医药科技有限公司025-66023220 15250997978 · [email protected]
上海诚合医药科技有限公司021-021-54382182 18601603956 · [email protected]
湖北摩科化学有限公司18627753421; 18627756402 · [email protected]
深圳市恒丰万达医药科技有限公司13986652530 · [email protected]
上海择睿生物科技有限公司021-54580889 18321124657 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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